KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6D
All Species:
31.52
Human Site:
T142
Identified Species:
77.04
UniProt:
O43924
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43924
NP_002592.1
150
17420
T142
D
D
D
L
L
V
S
T
S
R
V
R
L
F
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113642
150
17416
T142
D
D
D
L
L
V
S
T
S
R
V
R
L
F
Y
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55057
150
17329
T142
D
D
D
L
L
V
S
T
S
K
V
R
L
F
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514869
203
22624
T195
D
D
D
L
L
V
S
T
S
R
V
K
L
F
Y
Chicken
Gallus gallus
XP_422739
251
28154
T243
D
D
D
L
L
V
S
T
S
R
V
R
L
F
Y
Frog
Xenopus laevis
Q6INE2
241
27852
I228
Y
F
V
D
N
K
L
I
M
H
N
K
A
D
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLJ0
151
17385
K143
D
N
E
T
L
I
T
K
S
V
V
R
L
Y
Y
Honey Bee
Apis mellifera
XP_394004
147
16999
T139
D
D
D
L
L
V
S
T
S
K
V
R
L
F
Y
Nematode Worm
Caenorhab. elegans
Q18268
159
18353
T151
D
G
D
L
L
V
S
T
S
R
V
R
L
Y
Y
Sea Urchin
Strong. purpuratus
XP_001177685
147
16903
T139
D
E
E
L
L
V
S
T
S
K
V
R
L
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
N.A.
N.A.
98
N.A.
N.A.
65.5
57.7
20.3
N.A.
N.A.
61.5
81.3
64.7
76
Protein Similarity:
100
N.A.
100
N.A.
N.A.
99.3
N.A.
N.A.
70.9
58.9
36
N.A.
N.A.
78.8
92.6
83
89.3
P-Site Identity:
100
N.A.
100
N.A.
N.A.
93.3
N.A.
N.A.
93.3
100
6.6
N.A.
N.A.
46.6
93.3
86.6
73.3
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
13.3
N.A.
N.A.
80
100
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
90
60
70
10
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
20
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
60
0
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
0
10
0
30
0
20
0
0
0
% K
% Leu:
0
0
0
80
90
0
10
0
0
0
0
0
90
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
50
0
80
0
0
0
% R
% Ser:
0
0
0
0
0
0
80
0
90
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
0
0
10
80
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
80
0
0
0
10
90
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
30
100
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _