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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDE6D
All Species:
8.79
Human Site:
T68
Identified Species:
21.48
UniProt:
O43924
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43924
NP_002592.1
150
17420
T68
R
E
L
N
F
S
S
T
E
Q
M
E
K
F
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001113642
150
17416
T68
R
E
L
N
F
S
S
T
E
Q
M
E
K
F
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O55057
150
17329
A68
R
E
L
N
F
S
S
A
E
Q
M
E
K
F
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514869
203
22624
A121
R
E
L
N
F
S
S
A
E
Q
M
E
K
F
R
Chicken
Gallus gallus
XP_422739
251
28154
A169
R
E
L
N
F
S
S
A
E
Q
M
E
K
F
R
Frog
Xenopus laevis
Q6INE2
241
27852
D154
T
V
E
F
T
V
G
D
K
P
V
K
S
F
R
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VLJ0
151
17385
I69
R
E
I
N
F
S
T
I
E
S
M
E
N
F
R
Honey Bee
Apis mellifera
XP_394004
147
16999
A65
R
E
I
N
F
S
S
A
E
P
M
E
R
F
R
Nematode Worm
Caenorhab. elegans
Q18268
159
18353
S77
R
E
I
N
F
T
S
S
V
K
I
E
K
F
R
Sea Urchin
Strong. purpuratus
XP_001177685
147
16903
L65
R
E
V
N
F
S
S
L
E
P
M
H
Q
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.3
N.A.
N.A.
98
N.A.
N.A.
65.5
57.7
20.3
N.A.
N.A.
61.5
81.3
64.7
76
Protein Similarity:
100
N.A.
100
N.A.
N.A.
99.3
N.A.
N.A.
70.9
58.9
36
N.A.
N.A.
78.8
92.6
83
89.3
P-Site Identity:
100
N.A.
100
N.A.
N.A.
93.3
N.A.
N.A.
93.3
93.3
13.3
N.A.
N.A.
66.6
73.3
60
66.6
P-Site Similarity:
100
N.A.
100
N.A.
N.A.
93.3
N.A.
N.A.
93.3
93.3
33.3
N.A.
N.A.
80
86.6
93.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
40
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
90
10
0
0
0
0
0
80
0
0
80
0
0
0
% E
% Phe:
0
0
0
10
90
0
0
0
0
0
0
0
0
100
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
30
0
0
0
0
10
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
10
0
10
60
0
0
% K
% Leu:
0
0
50
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
80
0
0
0
0
% M
% Asn:
0
0
0
90
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
30
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
50
0
0
10
0
0
% Q
% Arg:
90
0
0
0
0
0
0
0
0
0
0
0
10
0
100
% R
% Ser:
0
0
0
0
0
80
80
10
0
10
0
0
10
0
0
% S
% Thr:
10
0
0
0
10
10
10
20
0
0
0
0
0
0
0
% T
% Val:
0
10
10
0
0
10
0
0
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _