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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ORC4L All Species: 28.18
Human Site: S313 Identified Species: 56.36
UniProt: O43929 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43929 NP_002543.2 436 50377 S313 S Q L C S M D S K A N I V H G
Chimpanzee Pan troglodytes XP_001159181 436 50421 S313 S Q L C S M D S K A N I V H G
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533348 436 50555 S313 N Q L C S M D S K A N I V H G
Cat Felis silvestris
Mouse Mus musculus O88708 433 49963 S310 Q H M C S L D S K A N I V H G
Rat Rattus norvegicus Q6P9Z8 434 50086 A311 Q H L C S L D A K A S I V H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511605 435 50275 S312 H Q L C S L D S K A S I V H G
Chicken Gallus gallus XP_422152 495 56654 S372 S K Q Y R M D S K A N I V H G
Frog Xenopus laevis O93479 432 49392 S311 F R L R N Q D S K A N I L H G
Zebra Danio Brachydanio rerio NP_998348 432 49308 S311 G R L I S A D S K A N V L H G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477320 459 51917 D335 G S Q F E G D D K I E L L C G
Honey Bee Apis mellifera XP_625030 451 52162 D332 S K M F S Q D D K V L M L E G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P54791 529 60687 N375 N K N Q L S N N L T G R L Q S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.2 N.A. 89.2 88.9 N.A. 82.1 67.2 72 65.5 N.A. 42.7 47 N.A. N.A.
Protein Similarity: 100 99.7 N.A. 97.4 N.A. 94.7 94.9 N.A. 91 76.9 84.8 81.6 N.A. 60.7 66 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 73.3 66.6 N.A. 80 73.3 60 60 N.A. 20 33.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 93.3 80 80 80 N.A. 33.3 60 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 9 0 75 0 0 0 0 0 % A
% Cys: 0 0 0 50 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 92 17 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 9 0 0 9 0 % E
% Phe: 9 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 0 0 0 0 9 0 0 0 0 9 0 0 0 92 % G
% His: 9 17 0 0 0 0 0 0 0 0 0 0 0 75 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 9 0 67 0 0 0 % I
% Lys: 0 25 0 0 0 0 0 0 92 0 0 0 0 0 0 % K
% Leu: 0 0 59 0 9 25 0 0 9 0 9 9 42 0 0 % L
% Met: 0 0 17 0 0 34 0 0 0 0 0 9 0 0 0 % M
% Asn: 17 0 9 0 9 0 9 9 0 0 59 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 17 34 17 9 0 17 0 0 0 0 0 0 0 9 0 % Q
% Arg: 0 17 0 9 9 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 34 9 0 0 67 9 0 67 0 0 17 0 0 0 9 % S
% Thr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 9 59 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _