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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ORC4L
All Species:
26.36
Human Site:
Y418
Identified Species:
52.73
UniProt:
O43929
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43929
NP_002543.2
436
50377
Y418
I
M
N
A
L
Q
K
Y
P
N
C
P
T
D
V
Chimpanzee
Pan troglodytes
XP_001159181
436
50421
Y418
I
M
N
A
L
Q
K
Y
P
N
C
P
T
D
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_533348
436
50555
Y418
I
M
N
A
L
Q
K
Y
P
N
C
P
T
D
V
Cat
Felis silvestris
Mouse
Mus musculus
O88708
433
49963
Y415
I
M
N
A
L
Q
K
Y
S
N
C
P
T
D
V
Rat
Rattus norvegicus
Q6P9Z8
434
50086
Y416
I
M
N
A
L
Q
K
Y
S
N
C
P
T
D
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511605
435
50275
Y417
I
M
D
A
L
Q
K
Y
P
N
C
P
T
D
V
Chicken
Gallus gallus
XP_422152
495
56654
Y477
I
M
D
A
L
Q
A
Y
P
N
C
P
T
D
V
Frog
Xenopus laevis
O93479
432
49392
L413
N
T
Q
I
V
E
A
L
Q
K
Y
P
N
C
P
Zebra Danio
Brachydanio rerio
NP_998348
432
49308
L413
H
G
Q
V
M
E
A
L
Q
R
Y
P
Q
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477320
459
51917
I436
L
A
L
T
Y
S
Q
I
H
H
C
M
Q
R
Y
Honey Bee
Apis mellifera
XP_625030
451
52162
V433
S
Q
Q
V
M
E
A
V
K
N
Y
S
G
L
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P54791
529
60687
F469
N
L
V
Q
L
D
F
F
T
E
K
S
A
V
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.2
N.A.
89.2
88.9
N.A.
82.1
67.2
72
65.5
N.A.
42.7
47
N.A.
N.A.
Protein Similarity:
100
99.7
N.A.
97.4
N.A.
94.7
94.9
N.A.
91
76.9
84.8
81.6
N.A.
60.7
66
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
86.6
6.6
6.6
N.A.
6.6
6.6
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
100
93.3
20
20
N.A.
26.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
59
0
0
34
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
67
0
0
17
0
% C
% Asp:
0
0
17
0
0
9
0
0
0
0
0
0
0
59
0
% D
% Glu:
0
0
0
0
0
25
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
9
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% G
% His:
9
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% H
% Ile:
59
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
50
0
9
9
9
0
0
0
0
% K
% Leu:
9
9
9
0
67
0
0
17
0
0
0
0
0
9
0
% L
% Met:
0
59
0
0
17
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
17
0
42
0
0
0
0
0
0
67
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
42
0
0
75
0
0
25
% P
% Gln:
0
9
25
9
0
59
9
0
17
0
0
0
17
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% R
% Ser:
9
0
0
0
0
9
0
0
17
0
0
17
0
0
0
% S
% Thr:
0
9
0
9
0
0
0
0
9
0
0
0
59
0
0
% T
% Val:
0
0
9
17
9
0
0
9
0
0
0
0
0
9
59
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
59
0
0
25
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _