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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKY
All Species:
43.33
Human Site:
Y253
Identified Species:
79.44
UniProt:
O43930
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43930
NP_005035
277
31708
Y253
D
D
N
P
F
G
I
Y
Q
K
I
L
A
G
K
Chimpanzee
Pan troglodytes
XP_001145269
358
40936
Y253
D
E
N
P
L
G
I
Y
Q
K
I
L
A
G
K
Rhesus Macaque
Macaca mulatta
XP_001086667
358
40973
Y253
D
D
N
P
F
G
I
Y
Q
K
I
L
A
G
K
Dog
Lupus familis
XP_852513
341
38934
Y236
D
D
N
P
F
G
I
Y
Q
K
I
L
A
G
K
Cat
Felis silvestris
Mouse
Mus musculus
Q922R0
355
40448
Y250
D
D
N
P
F
G
I
Y
Q
K
I
L
A
C
K
Rat
Rattus norvegicus
P68182
351
40689
Y248
A
D
Q
P
I
Q
I
Y
E
K
I
V
S
G
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514495
450
51108
Y345
D
D
N
P
F
G
I
Y
Q
K
I
L
A
G
K
Chicken
Gallus gallus
Q6U1I9
432
48872
Y307
S
R
N
T
A
E
M
Y
D
N
I
L
N
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7ZTW4
433
48964
Y308
S
R
N
T
A
E
M
Y
D
N
I
L
N
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P16912
583
65389
Y478
D
E
Q
P
F
G
I
Y
E
K
I
L
S
G
K
Honey Bee
Apis mellifera
XP_393711
374
42855
Y269
D
D
N
P
F
G
I
Y
E
K
I
L
S
G
R
Nematode Worm
Caenorhab. elegans
P21137
404
46327
Y285
A
D
Q
P
I
Q
I
Y
E
K
I
V
S
G
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
Y274
D
T
T
P
M
K
T
Y
E
K
I
L
Q
G
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.3
70.9
61.5
N.A.
56.3
37.8
N.A.
49.7
31.2
N.A.
30
N.A.
28.1
42.5
32.9
N.A.
Protein Similarity:
100
74.8
73.7
66.5
N.A.
64.2
54.4
N.A.
55.1
43
N.A.
44.1
N.A.
38.5
54
50.9
N.A.
P-Site Identity:
100
86.6
100
100
N.A.
93.3
53.3
N.A.
100
26.6
N.A.
26.6
N.A.
73.3
80
53.3
N.A.
P-Site Similarity:
100
93.3
100
100
N.A.
93.3
73.3
N.A.
100
33.3
N.A.
33.3
N.A.
93.3
100
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
16
0
0
0
0
0
0
0
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
70
62
0
0
0
0
0
0
16
0
0
0
0
0
0
% D
% Glu:
0
16
0
0
0
16
0
0
39
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
54
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
62
0
0
0
0
0
0
0
77
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
16
0
77
0
0
0
100
0
0
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
85
0
0
0
16
77
% K
% Leu:
0
0
0
0
8
0
0
0
0
0
0
85
0
0
0
% L
% Met:
0
0
0
0
8
0
16
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
70
0
0
0
0
0
0
16
0
0
16
0
0
% N
% Pro:
0
0
0
85
0
0
0
0
0
0
0
0
0
0
16
% P
% Gln:
0
0
24
0
0
16
0
0
47
0
0
0
8
0
0
% Q
% Arg:
0
16
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
16
0
0
0
0
0
0
0
0
0
0
0
31
0
0
% S
% Thr:
0
8
8
16
0
0
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _