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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX1 All Species: 20
Human Site: S1147 Identified Species: 27.5
UniProt: O43933 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43933 NP_000457.1 1283 142867 S1147 N G T S S D L S S Q C L S A P
Chimpanzee Pan troglodytes XP_519198 1283 142803 S1147 N G T S S D L S S Q C L S A P
Rhesus Macaque Macaca mulatta XP_001101055 1278 142022 S1142 N G T S S D L S S Q C L S A P
Dog Lupus familis XP_532459 1267 140567 S1131 N G T S S D L S P Q C L S A P
Cat Felis silvestris
Mouse Mus musculus Q5BL07 1284 141409 S1148 N G T P S D L S S H C L S A P
Rat Rattus norvegicus P46462 806 89330 D671 S P V A K D V D L E F L A K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520628 1178 126535 Y1041 R L Y F G S S Y E S E L G S G
Chicken Gallus gallus XP_418655 1290 143066 S1155 G T P S E L S S L C L S G P N
Frog Xenopus laevis P23787 805 89193 V670 K S P V A K D V D V D F L A K
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 D671 S P I S K D V D L D F L A K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 E666 R K S P L A K E V D L T Y I A
Honey Bee Apis mellifera XP_397107 1069 120490 D934 K V D T T G L D L K E L A T L
Nematode Worm Caenorhab. elegans P54812 810 89622 L675 K T P L S A D L D L N F L A K
Sea Urchin Strong. purpuratus XP_797089 1508 166130 T1372 P E G S V F D T T M T P A T P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCN8 815 90322 A680 D V D L R A L A K Y T Q G F S
Baker's Yeast Sacchar. cerevisiae P24004 1043 117258 F908 I A E K T A G F S G A D L Q G
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 G1236 R E L N A A A G P E G K Q I S
Conservation
Percent
Protein Identity: 100 99.6 92.8 86.4 N.A. 82 23.3 N.A. 52.4 62.4 22.9 22.8 N.A. 23.6 27.6 22.1 35.2
Protein Similarity: 100 100 94.9 92 N.A. 89.5 39.2 N.A. 66 77.6 38.6 39 N.A. 37.6 46.7 38.4 53.2
P-Site Identity: 100 100 100 93.3 N.A. 86.6 13.3 N.A. 6.6 13.3 6.6 20 N.A. 0 13.3 13.3 13.3
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 46.6 N.A. 13.3 13.3 13.3 40 N.A. 6.6 40 13.3 33.3
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.7 21.4
Protein Similarity: N.A. N.A. N.A. 38.5 45.2 40.9
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 0
P-Site Similarity: N.A. N.A. N.A. 20 13.3 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 6 0 6 12 30 6 6 0 0 6 0 24 42 6 % A
% Cys: 0 0 0 0 0 0 0 0 0 6 30 0 0 0 0 % C
% Asp: 6 0 12 0 0 42 18 18 12 12 6 6 0 0 0 % D
% Glu: 0 12 6 0 6 0 0 6 6 12 12 0 0 0 0 % E
% Phe: 0 0 0 6 0 6 0 6 0 0 12 12 0 6 0 % F
% Gly: 6 30 6 0 6 6 6 6 0 6 6 0 18 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 0 % H
% Ile: 6 0 6 0 0 0 0 0 0 0 0 0 0 12 0 % I
% Lys: 18 6 0 6 12 6 6 0 6 6 0 6 0 12 12 % K
% Leu: 0 6 6 12 6 6 42 6 24 6 12 53 18 0 6 % L
% Met: 0 0 0 0 0 0 0 0 0 6 0 0 0 0 12 % M
% Asn: 30 0 0 6 0 0 0 0 0 0 6 0 0 0 6 % N
% Pro: 6 12 18 12 0 0 0 0 12 0 0 6 0 6 36 % P
% Gln: 0 0 0 0 0 0 0 0 0 24 0 6 6 6 0 % Q
% Arg: 18 0 0 0 6 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 12 6 6 42 36 6 12 36 30 6 0 6 30 6 12 % S
% Thr: 0 12 30 6 12 0 0 6 6 0 12 6 0 12 0 % T
% Val: 0 12 6 6 6 0 12 6 6 6 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 6 0 0 0 0 6 0 6 0 0 6 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _