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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX1 All Species: 24.55
Human Site: S1216 Identified Species: 33.75
UniProt: O43933 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43933 NP_000457.1 1283 142867 S1216 S Q S G E D E S M N Q P G P I
Chimpanzee Pan troglodytes XP_519198 1283 142803 S1216 S Q S G E D E S I N Q P G P I
Rhesus Macaque Macaca mulatta XP_001101055 1278 142022 S1211 S Q S G E D E S I N Q P G P I
Dog Lupus familis XP_532459 1267 140567 S1200 S Q S G E E D S L H Q P G P V
Cat Felis silvestris
Mouse Mus musculus Q5BL07 1284 141409 S1217 S Q S G E D E S L N Q P G P I
Rat Rattus norvegicus P46462 806 89330 M740 R D H F E E A M R F A R R S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520628 1178 126535 P1110 S P S R D E E P V C G P G P A
Chicken Gallus gallus XP_418655 1290 143066 T1224 S K N G E D S T L N Q S V L A
Frog Xenopus laevis P23787 805 89193 A739 R R D H F E E A M R F A R R S
Zebra Danio Brachydanio rerio Q7ZU99 806 89405 M740 K D H F E E A M R F A R R S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KN62 801 88841 E735 E I T S A H F E E A M K F A R
Honey Bee Apis mellifera XP_397107 1069 120490 C1003 E T A W M V V C Q C A R V E V
Nematode Worm Caenorhab. elegans P54812 810 89622 H744 V P E I T R A H F E E A M K F
Sea Urchin Strong. purpuratus XP_797089 1508 166130 T1441 G E S V G G P T D D T V T E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCN8 815 90322 S749 S M K Y A R R S V S D A D I R
Baker's Yeast Sacchar. cerevisiae P24004 1043 117258 S977 V V H E T K T S T S A A S E L
Red Bread Mold Neurospora crassa Q7SGP2 1381 148356 A1305 K D K K K E G A G G D G N G V
Conservation
Percent
Protein Identity: 100 99.6 92.8 86.4 N.A. 82 23.3 N.A. 52.4 62.4 22.9 22.8 N.A. 23.6 27.6 22.1 35.2
Protein Similarity: 100 100 94.9 92 N.A. 89.5 39.2 N.A. 66 77.6 38.6 39 N.A. 37.6 46.7 38.4 53.2
P-Site Identity: 100 93.3 93.3 66.6 N.A. 93.3 6.6 N.A. 40 40 13.3 6.6 N.A. 0 0 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 60 66.6 33.3 20 N.A. 6.6 13.3 6.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. 23.5 25.7 21.4
Protein Similarity: N.A. N.A. N.A. 38.5 45.2 40.9
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 0
P-Site Similarity: N.A. N.A. N.A. 26.6 20 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 0 12 0 18 12 0 6 24 24 0 6 12 % A
% Cys: 0 0 0 0 0 0 0 6 0 12 0 0 0 0 0 % C
% Asp: 0 18 6 0 6 30 6 0 6 6 12 0 6 0 0 % D
% Glu: 12 6 6 6 48 36 36 6 6 6 6 0 0 18 6 % E
% Phe: 0 0 0 12 6 0 6 0 6 12 6 0 6 0 6 % F
% Gly: 6 0 0 36 6 6 6 0 6 6 6 6 36 6 0 % G
% His: 0 0 18 6 0 6 0 6 0 6 0 0 0 0 0 % H
% Ile: 0 6 0 6 0 0 0 0 12 0 0 0 0 6 24 % I
% Lys: 12 6 12 6 6 6 0 0 0 0 0 6 0 6 0 % K
% Leu: 0 0 0 0 0 0 0 0 18 0 0 0 0 6 6 % L
% Met: 0 6 0 0 6 0 0 12 12 0 6 0 6 0 0 % M
% Asn: 0 0 6 0 0 0 0 0 0 30 0 0 6 0 0 % N
% Pro: 0 12 0 0 0 0 6 6 0 0 0 36 0 36 0 % P
% Gln: 0 30 0 0 0 0 0 0 6 0 36 0 0 0 0 % Q
% Arg: 12 6 0 6 0 12 6 0 12 6 0 18 18 6 12 % R
% Ser: 48 0 42 6 0 0 6 42 0 12 0 6 6 12 6 % S
% Thr: 0 6 6 0 12 0 6 12 6 0 6 0 6 0 0 % T
% Val: 12 6 0 6 0 6 6 0 12 0 0 6 12 0 30 % V
% Trp: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _