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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TIMM8A All Species: 11.38
Human Site: S4 Identified Species: 15.64
UniProt: O60220 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60220 NP_004076.1 97 10998 S4 _ _ _ _ M D S S S S S S A A G
Chimpanzee Pan troglodytes XP_001146364 83 9325
Rhesus Macaque Macaca mulatta XP_001095067 139 15567 S46 G R P G V D S S S S S S A A G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WVA2 97 11024 S4 _ _ _ _ M E S S T S S S G S A
Rat Rattus norvegicus Q9WVA1 97 11024 S4 _ _ _ _ M E S S S S S S G S A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511200 96 10843 P4 _ _ _ _ M D A P A A V A G A S
Chicken Gallus gallus XP_420185 94 10668 P4 _ _ _ _ M E A P S G G G L G G
Frog Xenopus laevis Q66L32 94 10390 D5 _ _ _ M S D F D S N L D L A G
Zebra Danio Brachydanio rerio Q6DEM5 90 10544 Q4 _ _ _ _ M D T Q G V A T D P Q
Tiger Blowfish Takifugu rubipres Q90YI5 90 10442 Q4 _ _ _ _ M N G Q G A S A D P Q
Fruit Fly Dros. melanogaster Q9Y1A3 88 10044
Honey Bee Apis mellifera XP_001122230 86 9800
Nematode Worm Caenorhab. elegans Q9N408 83 9559
Sea Urchin Strong. purpuratus XP_001183127 89 10035 Q4 _ _ _ _ M A Q Q G G V D P E M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XGY4 77 8732
Baker's Yeast Sacchar. cerevisiae P57744 87 9745
Red Bread Mold Neurospora crassa Q9Y8C0 92 10401 P4 _ _ _ _ M D I P Q A D L D L L
Conservation
Percent
Protein Identity: 100 38.1 69 N.A. N.A. 94.8 94.8 N.A. 88.6 85.5 41.2 75.2 73.2 39.1 40.2 34 45.3
Protein Similarity: 100 52.5 69 N.A. N.A. 97.9 96.9 N.A. 92.7 87.6 58.7 84.5 83.5 50.5 54.6 51.5 67
P-Site Identity: 100 0 66.6 N.A. N.A. 54.5 63.6 N.A. 27.2 27.2 33.3 18.1 18.1 0 0 0 9
P-Site Similarity: 100 0 86.6 N.A. N.A. 81.8 81.8 N.A. 63.6 45.4 41.6 45.4 45.4 0 0 0 9
Percent
Protein Identity: N.A. N.A. N.A. 27.8 31.9 34
Protein Similarity: N.A. N.A. N.A. 49.4 49.4 47.4
P-Site Identity: N.A. N.A. N.A. 0 0 18.1
P-Site Similarity: N.A. N.A. N.A. 0 0 27.2
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 6 12 0 6 18 6 12 12 24 12 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 36 0 6 0 0 6 12 18 0 0 % D
% Glu: 0 0 0 0 0 18 0 0 0 0 0 0 0 6 0 % E
% Phe: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % F
% Gly: 6 0 0 6 0 0 6 0 18 12 6 6 18 6 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 6 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 6 6 12 6 6 % L
% Met: 0 0 0 6 53 0 0 0 0 0 0 0 0 0 6 % M
% Asn: 0 0 0 0 0 6 0 0 0 6 0 0 0 0 0 % N
% Pro: 0 0 6 0 0 0 0 18 0 0 0 0 6 12 0 % P
% Gln: 0 0 0 0 0 0 6 18 6 0 0 0 0 0 12 % Q
% Arg: 0 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 6 0 24 24 30 24 30 24 0 12 6 % S
% Thr: 0 0 0 0 0 0 6 0 6 0 0 6 0 0 0 % T
% Val: 0 0 0 0 6 0 0 0 0 6 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 59 59 59 53 0 0 0 0 0 0 0 0 0 0 0 % _