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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KALRN All Species: 15.76
Human Site: S2391 Identified Species: 38.52
UniProt: O60229 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60229 NP_003938.1 2985 340174 S2391 T K A T A A E S S D G S I K K
Chimpanzee Pan troglodytes XP_516703 2991 340419 S2397 T K A T A A E S S D G S I K K
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535768 3009 341980 N2415 K A T A A A E N S D G S I K K
Cat Felis silvestris
Mouse Mus musculus A2CG49 2964 336982 S2364 K A T A A A E S S D G S I K K
Rat Rattus norvegicus P97924 2959 336568 S2365 K A T A P A E S S D E S I K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519275 3047 344048 S2437 Q K G G S F W S S I P A S P A
Chicken Gallus gallus XP_001234055 3038 345602 N2444 L T K P T T D N S D G S I K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q1LUA6 3028 342343 S2411 T G S S S F W S S V P A S P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651960 2263 256958 S1740 M Q D Q S N R S K A D A L S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783478 2887 322988 R2317 G P T Q H Q S R G G D S P A P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 N.A. 97.4 N.A. 97 97 N.A. 61.7 91.8 N.A. 60.9 N.A. 34 N.A. N.A. 21.2
Protein Similarity: 100 98.8 N.A. 98.3 N.A. 98.3 98.3 N.A. 76.4 95.2 N.A. 75.3 N.A. 50.8 N.A. N.A. 39.9
P-Site Identity: 100 100 N.A. 66.6 N.A. 73.3 60 N.A. 20 46.6 N.A. 20 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 100 N.A. 73.3 N.A. 73.3 60 N.A. 33.3 60 N.A. 46.6 N.A. 33.3 N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 30 20 30 40 50 0 0 0 10 0 30 0 10 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 10 0 0 60 20 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 50 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 10 10 0 0 0 0 10 10 50 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 0 0 60 0 0 % I
% Lys: 30 30 10 0 0 0 0 0 10 0 0 0 0 60 60 % K
% Leu: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 20 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 10 10 0 0 0 0 0 20 0 10 20 10 % P
% Gln: 10 10 0 20 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 10 30 0 10 70 80 0 0 70 20 10 10 % S
% Thr: 30 10 40 20 10 10 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 20 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _