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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX16
All Species:
19.39
Human Site:
S116
Identified Species:
32.82
UniProt:
O60231
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60231
NP_003578.2
1041
119264
S116
E
T
V
S
R
A
G
S
S
L
Q
K
K
R
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
S116
E
T
V
S
R
A
G
S
S
L
Q
K
K
R
K
Rhesus Macaque
Macaca mulatta
NP_001098636
1044
119602
S116
E
T
V
S
R
A
G
S
S
L
Q
K
K
R
K
Dog
Lupus familis
XP_538827
1042
119346
S116
E
T
V
G
R
T
G
S
S
L
Q
K
K
R
R
Cat
Felis silvestris
Mouse
Mus musculus
A2A4P0
1244
142553
S155
E
L
E
A
L
M
P
S
A
A
G
Q
E
K
Q
Rat
Rattus norvegicus
NP_997661
1044
119245
S116
A
V
A
R
D
G
S
S
L
Q
K
K
R
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZI74
1231
137685
K119
K
K
V
T
L
H
I
K
W
P
K
N
V
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_956318
1054
121479
E113
A
A
R
E
G
G
K
E
K
K
S
K
E
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609946
894
102815
R88
H
L
R
L
Q
S
R
R
Q
Y
L
E
K
R
K
Honey Bee
Apis mellifera
XP_001122325
831
95330
I25
E
E
R
R
K
K
D
I
K
E
R
D
E
F
A
Nematode Worm
Caenorhab. elegans
O45244
1008
114272
T108
Y
S
A
S
S
T
K
T
K
N
V
R
K
R
K
Sea Urchin
Strong. purpuratus
O17438
455
51461
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
R116
E
L
E
K
E
I
E
R
E
A
E
E
R
R
R
Baker's Yeast
Sacchar. cerevisiae
P24384
1145
129992
A155
L
P
S
T
K
I
P
A
K
I
E
A
K
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.4
97.2
N.A.
39.5
95.9
N.A.
N.A.
24.7
N.A.
72.7
N.A.
57
53.9
55.8
24.5
Protein Similarity:
100
99.7
99.5
98.8
N.A.
57.7
97.8
N.A.
N.A.
41.3
N.A.
85.6
N.A.
71.7
66.4
75.2
33.1
P-Site Identity:
100
100
100
80
N.A.
13.3
13.3
N.A.
N.A.
6.6
N.A.
13.3
N.A.
20
6.6
26.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
53.3
40
N.A.
N.A.
26.6
N.A.
20
N.A.
40
26.6
46.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
36.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
59.5
57.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
15
8
0
22
0
8
8
15
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
8
0
0
0
0
8
0
0
8
% D
% Glu:
50
8
15
8
8
0
8
8
8
8
15
15
22
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
8
8
15
29
0
0
0
8
0
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
15
8
8
0
8
0
0
0
8
0
% I
% Lys:
8
8
0
8
15
8
15
8
29
8
15
43
50
15
36
% K
% Leu:
8
22
0
8
15
0
0
0
8
29
8
0
0
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
15
0
0
8
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
8
8
29
8
0
0
8
% Q
% Arg:
0
0
22
15
29
0
8
15
0
0
8
8
15
58
22
% R
% Ser:
0
8
8
29
8
8
8
43
29
0
8
0
0
0
0
% S
% Thr:
0
29
0
15
0
15
0
8
0
0
0
0
0
0
0
% T
% Val:
0
8
36
0
0
0
0
0
0
0
8
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _