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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX16 All Species: 31.21
Human Site: S488 Identified Species: 52.82
UniProt: O60231 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60231 NP_003578.2 1041 119264 S488 I R F E D C T S E R T V L R Y
Chimpanzee Pan troglodytes Q7YR39 1044 119631 S491 I R F E D C T S E R T V L R Y
Rhesus Macaque Macaca mulatta NP_001098636 1044 119602 S491 I R F E D C T S E R T V L R Y
Dog Lupus familis XP_538827 1042 119346 S489 I R F E D C T S E R T V L R Y
Cat Felis silvestris
Mouse Mus musculus A2A4P0 1244 142553 S677 I R F E D C T S P E T V I K Y
Rat Rattus norvegicus NP_997661 1044 119245 S491 I R F E D C T S E R T V L R Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI74 1231 137685 A571 R L E S K P P A R G G A L L F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_956318 1054 121479 S501 I R F E D C T S E R T I L K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609946 894 102815 P397 K D I A R F R P E L K L L I S
Honey Bee Apis mellifera XP_001122325 831 95330 L334 I T K F R T D L K L L I S S A
Nematode Worm Caenorhab. elegans O45244 1008 114272 S453 I R F E D C T S E K T V L K Y
Sea Urchin Strong. purpuratus O17438 455 51461
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 G603 I R F E D C T G P D T V I K Y
Baker's Yeast Sacchar. cerevisiae P24384 1145 129992 G571 I R F E D V T G P D T R I K Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.4 97.2 N.A. 39.5 95.9 N.A. N.A. 24.7 N.A. 72.7 N.A. 57 53.9 55.8 24.5
Protein Similarity: 100 99.7 99.5 98.8 N.A. 57.7 97.8 N.A. N.A. 41.3 N.A. 85.6 N.A. 71.7 66.4 75.2 33.1
P-Site Identity: 100 100 100 100 N.A. 73.3 100 N.A. N.A. 6.6 N.A. 86.6 N.A. 13.3 6.6 86.6 0
P-Site Similarity: 100 100 100 100 N.A. 86.6 100 N.A. N.A. 20 N.A. 100 N.A. 20 20 100 0
Percent
Protein Identity: N.A. N.A. N.A. 40 36.5 N.A.
Protein Similarity: N.A. N.A. N.A. 59.5 57.9 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 80 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 0 0 8 0 0 8 % A
% Cys: 0 0 0 0 0 65 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 72 0 8 0 0 15 0 0 0 0 0 % D
% Glu: 0 0 8 72 0 0 0 0 58 8 0 0 0 0 0 % E
% Phe: 0 0 72 8 0 8 0 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 15 0 8 8 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 79 0 8 0 0 0 0 0 0 0 0 15 22 8 0 % I
% Lys: 8 0 8 0 8 0 0 0 8 8 8 0 0 36 0 % K
% Leu: 0 8 0 0 0 0 0 8 0 15 8 8 65 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 8 8 22 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 8 72 0 0 15 0 8 0 8 43 0 8 0 36 0 % R
% Ser: 0 0 0 8 0 0 0 58 0 0 0 0 8 8 8 % S
% Thr: 0 8 0 0 0 8 72 0 0 0 72 0 0 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 58 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 72 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _