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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SH3BP5 All Species: 11.52
Human Site: T420 Identified Species: 25.33
UniProt: O60239 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60239 NP_004835.2 455 50425 T420 S S K S Q S S T S P E G Q A L
Chimpanzee Pan troglodytes XP_526142 535 58438 N509 D R A E G A E N K T S D K A N
Rhesus Macaque Macaca mulatta XP_001107738 393 43463 E367 H V S L D G Q E L G T R S G G
Dog Lupus familis XP_542777 466 51639 T431 S G K S Q S N T S R E G Q A L
Cat Felis silvestris
Mouse Mus musculus Q9Z131 463 51788 T423 R S R S Q S S T S L E S Q A L
Rat Rattus norvegicus Q91Y80 457 50810 T422 R S R S Q S S T S L E G Q A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514506 721 77859 D694 A T E G P T L D N R M K R L S
Chicken Gallus gallus NP_001026160 431 47779 K401 L A L D N R M K Q L S L Q C M
Frog Xenopus laevis Q5U584 373 41573 V347 D G R E T G A V E S G G S R E
Zebra Danio Brachydanio rerio NP_998623 446 49847 N398 L N N N S I S N A K T T F G L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V785 476 53619 P421 H Q L N H L A P P T P I K K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.2 34.2 87.1 N.A. 90.5 92.7 N.A. 53.5 76.4 32.5 67.2 N.A. 34.8 N.A. N.A. N.A.
Protein Similarity: 100 76.4 51.6 89 N.A. 93.3 94.9 N.A. 56.8 83 48.7 76.2 N.A. 50.8 N.A. N.A. N.A.
P-Site Identity: 100 6.6 0 80 N.A. 73.3 80 N.A. 0 6.6 6.6 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 20 0 86.6 N.A. 80 86.6 N.A. 40 20 20 33.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 0 0 10 19 0 10 0 0 0 0 46 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 19 0 0 10 10 0 0 10 0 0 0 10 0 0 0 % D
% Glu: 0 0 10 19 0 0 10 10 10 0 37 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 19 0 10 10 19 0 0 0 10 10 37 0 19 10 % G
% His: 19 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 19 0 0 0 0 10 10 10 0 10 19 10 0 % K
% Leu: 19 0 19 10 0 10 10 0 10 28 0 10 0 10 55 % L
% Met: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 10 % M
% Asn: 0 10 10 19 10 0 10 19 10 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 10 0 0 10 10 10 10 0 0 0 0 % P
% Gln: 0 10 0 0 37 0 10 0 10 0 0 0 46 0 0 % Q
% Arg: 19 10 28 0 0 10 0 0 0 19 0 10 10 10 0 % R
% Ser: 19 28 10 37 10 37 37 0 37 10 19 10 19 0 10 % S
% Thr: 0 10 0 0 10 10 0 37 0 19 19 10 0 0 0 % T
% Val: 0 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _