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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HS6ST1 All Species: 10.61
Human Site: S169 Identified Species: 25.93
UniProt: O60243 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60243 NP_004798.3 411 48226 S169 G V L D R R D S A A L R T P R
Chimpanzee Pan troglodytes XP_001141653 452 52346 R210 C P S H T K S R S V A Q A G K
Rhesus Macaque Macaca mulatta XP_001105734 683 76085 S441 G V L D R R D S A A L R T P R
Dog Lupus familis XP_852618 606 68909 D309 A V V D G K R D A R L R P S R
Cat Felis silvestris
Mouse Mus musculus Q9QYK5 411 48284 P169 G V L D R R D P A G L R S P R
Rat Rattus norvegicus NP_001101680 329 38999 I99 S P R K F Y Y I T L L R D P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512595 484 55776 S242 L M E K K D C S R N H S R A R
Chicken Gallus gallus Q76KB2 408 48073 S166 G V L G R R E S A P N R T P R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q56UJ5 413 48891 E167 P G V L N K K E S R M K N Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794153 394 46055 T158 W L F S R M S T G W L C G L H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.9 60.1 44.5 N.A. 97.3 77.8 N.A. 54.5 89.5 N.A. 80.1 N.A. N.A. N.A. N.A. 44
Protein Similarity: 100 90.9 60.1 55.7 N.A. 98.3 78.8 N.A. 64 93.9 N.A. 88.6 N.A. N.A. N.A. N.A. 59.6
P-Site Identity: 100 0 100 40 N.A. 80 20 N.A. 13.3 73.3 N.A. 6.6 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 53.3 N.A. 86.6 20 N.A. 26.6 80 N.A. 40 N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 50 20 10 0 10 10 0 % A
% Cys: 10 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 40 0 10 30 10 0 0 0 0 10 0 0 % D
% Glu: 0 0 10 0 0 0 10 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 10 0 10 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 40 10 0 10 10 0 0 0 10 10 0 0 10 10 0 % G
% His: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 10 % H
% Ile: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 20 10 30 10 0 0 0 0 10 0 0 10 % K
% Leu: 10 10 40 10 0 0 0 0 0 10 60 0 0 10 0 % L
% Met: 0 10 0 0 0 10 0 0 0 0 10 0 0 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 10 10 0 10 0 0 % N
% Pro: 10 20 0 0 0 0 0 10 0 10 0 0 10 50 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % Q
% Arg: 0 0 10 0 50 40 10 10 10 20 0 60 10 0 70 % R
% Ser: 10 0 10 10 0 0 20 40 20 0 0 10 10 10 0 % S
% Thr: 0 0 0 0 10 0 0 10 10 0 0 0 30 0 0 % T
% Val: 0 50 20 0 0 0 0 0 0 10 0 0 0 0 10 % V
% Trp: 10 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _