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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPSAP2 All Species: 29.7
Human Site: S227 Identified Species: 59.39
UniProt: O60256 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60256 NP_002758.1 369 40926 S227 D L V D G R H S P P M V R S V
Chimpanzee Pan troglodytes XP_001155536 369 40864 S227 D L V D G R H S P P M V R S V
Rhesus Macaque Macaca mulatta XP_001104513 385 42500 H243 L D M D D G R H S P P M V K N
Dog Lupus familis XP_864392 388 42749 S227 D L V D G R H S P P M V R S V
Cat Felis silvestris
Mouse Mus musculus Q8R574 369 40862 S227 D L V D G R H S P P M V R S V
Rat Rattus norvegicus O08618 369 40848 S227 D L V D G R H S P P M V R S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515604 270 29719 C137 K L L A S M M C K A G L T H L
Chicken Gallus gallus Q5ZL26 369 40785 S227 D M V D G R H S P P T A K N V
Frog Xenopus laevis Q7ZXC9 318 34683 L185 V T S I A D R L N V E F A L I
Zebra Danio Brachydanio rerio NP_998661 357 39510 S215 D L V D G R H S P P T V K N I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624652 354 39047 S213 D M N D G R Y S P P A L A S R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38689 320 35105 L187 A A T L A D R L D L N F A L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 73.2 94 N.A. 98.9 99.1 N.A. 69.6 95.6 43.6 89.6 N.A. N.A. 68.8 N.A. N.A.
Protein Similarity: 100 99.7 85.4 94.5 N.A. 99.4 99.4 N.A. 71.2 97 61.2 94.5 N.A. N.A. 82.3 N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 6.6 66.6 0 73.3 N.A. N.A. 53.3 N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 26.6 86.6 6.6 93.3 N.A. N.A. 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 39.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 58.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 9 17 0 0 0 0 9 9 9 25 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 67 9 0 75 9 17 0 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 17 0 0 0 % F
% Gly: 0 0 0 0 67 9 0 0 0 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 59 9 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 25 % I
% Lys: 9 0 0 0 0 0 0 0 9 0 0 0 17 9 0 % K
% Leu: 9 59 9 9 0 0 0 17 0 9 0 17 0 17 9 % L
% Met: 0 17 9 0 0 9 9 0 0 0 42 9 0 0 0 % M
% Asn: 0 0 9 0 0 0 0 0 9 0 9 0 0 17 9 % N
% Pro: 0 0 0 0 0 0 0 0 67 75 9 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 67 25 0 0 0 0 0 42 0 9 % R
% Ser: 0 0 9 0 9 0 0 67 9 0 0 0 0 50 0 % S
% Thr: 0 9 9 0 0 0 0 0 0 0 17 0 9 0 0 % T
% Val: 9 0 59 0 0 0 0 0 0 9 0 50 9 0 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _