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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KLK8 All Species: 24.85
Human Site: T70 Identified Species: 78.1
UniProt: O60259 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60259 NP_009127.1 260 28048 T70 V G G N W V L T A A H C K K P
Chimpanzee Pan troglodytes XP_001174106 305 32964 T115 V G G N W V L T A A H C K K P
Rhesus Macaque Macaca mulatta XP_001116177 242 26567 S54 I S P H W V L S A A H C Q T R
Dog Lupus familis XP_541468 259 28217 T70 I E D N W V L T A A H C K K R
Cat Felis silvestris
Mouse Mus musculus Q61955 260 28505 T70 V G D R W V L T A A H C K K Q
Rat Rattus norvegicus O88780 260 28491 T70 V G D R W V L T A A H C K K D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90629 248 26604 S62 I N S Q W V L S A A H C Y K S
Frog Xenopus laevis P70059 244 26061 S58 I N S Q W V V S A A H C Y K S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.2 45.7 77.6 N.A. 71.9 71.5 N.A. N.A. 41.1 40 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 85.2 62.3 86.5 N.A. 84.6 85 N.A. N.A. 58.8 57.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 46.6 73.3 N.A. 80 80 N.A. N.A. 53.3 46.6 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 73.3 80 N.A. 80 80 N.A. N.A. 66.6 66.6 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 100 100 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % C
% Asp: 0 0 38 0 0 0 0 0 0 0 0 0 0 0 13 % D
% Glu: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 50 25 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 13 0 0 0 0 0 0 100 0 0 0 0 % H
% Ile: 50 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 63 88 0 % K
% Leu: 0 0 0 0 0 0 88 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 25 0 38 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 25 % P
% Gln: 0 0 0 25 0 0 0 0 0 0 0 0 13 0 13 % Q
% Arg: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 25 % R
% Ser: 0 13 25 0 0 0 0 38 0 0 0 0 0 0 25 % S
% Thr: 0 0 0 0 0 0 0 63 0 0 0 0 0 13 0 % T
% Val: 50 0 0 0 0 100 13 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _