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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF5C All Species: 22.42
Human Site: S709 Identified Species: 35.24
UniProt: O60282 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60282 NP_004513.1 957 109495 S709 A L E Q Q M E S H R E A H Q K
Chimpanzee Pan troglodytes XP_525938 860 98662 E650 Q K L Q L E Q E K L S S D Y N
Rhesus Macaque Macaca mulatta XP_001082054 860 98340 E650 Q K L Q L E Q E K L S S D Y N
Dog Lupus familis XP_533351 955 109129 S707 A L E Q Q M E S H R E A H Q K
Cat Felis silvestris
Mouse Mus musculus P28738 956 109222 S708 A L E Q Q M E S H R E A H Q K
Rat Rattus norvegicus Q6QLM7 1027 116897 N705 A L E L Q M E N H R E A H H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508129 965 109909 D721 K Q I S S L R D E V D A K E K
Chicken Gallus gallus Q90640 1225 138905 S826 S L S K Q I E S L E T E M E L
Frog Xenopus laevis Q91784 1226 138905 S823 S V T K Q I E S L E T E M E L
Zebra Danio Brachydanio rerio NP_001116747 985 113653 S704 A L E Q Q M E S H R E T H Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P17210 975 110381 R735 E L R E A H T R Q V S E L R D
Honey Bee Apis mellifera XP_395236 988 112484 Q728 A L E E Q M D Q L R D A H Q K
Nematode Worm Caenorhab. elegans P34540 815 91875 V626 E A K L A A D V A R V E S G Q
Sea Urchin Strong. purpuratus P35978 1031 117504 S702 S M S E Q M E S H R D A H Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 G723 R V K A G G A G V A M A N G K
Conservation
Percent
Protein Identity: 100 89.8 85.5 98.3 N.A. 98 69.8 N.A. 75.2 26.3 24.8 76.8 N.A. 62 63.2 45.3 61.4
Protein Similarity: 100 89.8 86.4 98.9 N.A. 99.1 81.6 N.A. 86.4 45.3 45.5 86.9 N.A. 77.6 77.9 61.3 74.7
P-Site Identity: 100 6.6 6.6 100 N.A. 100 73.3 N.A. 13.3 26.6 20 93.3 N.A. 6.6 66.6 6.6 66.6
P-Site Similarity: 100 20 20 100 N.A. 100 86.6 N.A. 33.3 53.3 53.3 93.3 N.A. 20 86.6 26.6 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 31.7
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 52.5
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 40 7 0 7 14 7 7 0 7 7 0 54 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 14 7 0 0 20 0 14 0 7 % D
% Glu: 14 0 40 20 0 14 54 14 7 14 34 27 0 20 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 7 0 7 0 0 0 0 0 14 0 % G
% His: 0 0 0 0 0 7 0 0 40 0 0 0 47 7 0 % H
% Ile: 0 0 7 0 0 14 0 0 0 0 0 0 0 0 0 % I
% Lys: 7 14 14 14 0 0 0 0 14 0 0 0 7 0 54 % K
% Leu: 0 54 14 14 14 7 0 0 20 14 0 0 7 0 14 % L
% Met: 0 7 0 0 0 47 0 0 0 0 7 0 14 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 0 0 0 0 7 0 14 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 14 7 0 40 60 0 14 7 7 0 0 0 0 40 7 % Q
% Arg: 7 0 7 0 0 0 7 7 0 54 0 0 0 7 7 % R
% Ser: 20 0 14 7 7 0 0 47 0 0 20 14 7 0 0 % S
% Thr: 0 0 7 0 0 0 7 0 0 0 14 7 0 0 0 % T
% Val: 0 14 0 0 0 0 0 7 7 14 7 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 14 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _