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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
37.58
Human Site:
T275
Identified Species:
59.05
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
T275
A
L
A
E
G
T
K
T
H
V
P
Y
R
D
S
Chimpanzee
Pan troglodytes
XP_525938
860
98662
E250
E
E
W
K
K
K
Y
E
K
E
K
E
K
N
K
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
A249
V
T
M
W
S
K
K
A
S
V
P
F
T
K
T
Dog
Lupus familis
XP_533351
955
109129
T274
A
L
A
E
G
T
K
T
H
V
P
Y
R
D
S
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
T275
A
L
A
E
G
T
K
T
H
V
P
Y
R
D
S
Rat
Rattus norvegicus
Q6QLM7
1027
116897
S275
A
L
A
E
G
T
K
S
Y
V
P
Y
R
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
T273
S
A
L
A
E
S
S
T
Y
V
P
Y
R
D
S
Chicken
Gallus gallus
Q90640
1225
138905
G286
G
E
E
N
K
K
G
G
F
V
P
Y
R
D
S
Frog
Xenopus laevis
Q91784
1226
138905
G285
G
D
E
S
K
K
G
G
F
V
P
Y
R
D
S
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
T274
A
L
A
E
G
T
K
T
H
V
P
Y
R
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
T281
A
L
A
D
G
N
K
T
H
I
P
Y
R
D
S
Honey Bee
Apis mellifera
XP_395236
988
112484
T285
A
L
A
D
G
N
K
T
H
I
P
Y
R
D
S
Nematode Worm
Caenorhab. elegans
P34540
815
91875
K229
T
K
K
Q
L
T
G
K
L
Y
L
V
D
L
A
Sea Urchin
Strong. purpuratus
P35978
1031
117504
S273
A
L
A
D
G
K
K
S
H
I
P
Y
R
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
S278
A
L
T
D
G
K
S
S
H
V
P
Y
R
D
S
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
0
20
100
N.A.
100
86.6
N.A.
46.6
40
40
100
N.A.
80
80
6.6
73.3
P-Site Similarity:
100
20
33.3
100
N.A.
100
100
N.A.
66.6
40
40
100
N.A.
93.3
93.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
80
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
60
7
54
7
0
0
0
7
0
0
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
27
0
0
0
0
0
0
0
0
7
80
0
% D
% Glu:
7
14
14
34
7
0
0
7
0
7
0
7
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
14
0
0
7
0
0
0
% F
% Gly:
14
0
0
0
60
0
20
14
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
54
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% I
% Lys:
0
7
7
7
20
40
60
7
7
0
7
0
7
7
7
% K
% Leu:
0
60
7
0
7
0
0
0
7
0
7
0
0
7
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
14
0
0
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
87
0
0
0
0
% P
% Gln:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% R
% Ser:
7
0
0
7
7
7
14
20
7
0
0
0
0
0
80
% S
% Thr:
7
7
7
0
0
40
0
47
0
0
0
0
7
0
7
% T
% Val:
7
0
0
0
0
0
0
0
0
67
0
7
0
0
0
% V
% Trp:
0
0
7
7
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
0
14
7
0
80
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _