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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ST18
All Species:
21.82
Human Site:
Y672
Identified Species:
60
UniProt:
O60284
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60284
NP_055497.1
1047
115155
Y672
G
W
D
T
P
I
N
Y
S
K
T
H
G
K
T
Chimpanzee
Pan troglodytes
XP_528132
1047
115198
Y672
G
W
D
T
P
I
N
Y
S
K
T
H
G
K
T
Rhesus Macaque
Macaca mulatta
XP_001096064
1018
113743
R665
F
Q
E
A
L
E
E
R
R
Y
P
G
E
V
T
Dog
Lupus familis
XP_544076
1031
113415
Y656
G
W
D
T
P
I
N
Y
S
K
T
H
G
K
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80TY4
1045
114732
Y670
G
W
N
V
P
I
N
Y
S
K
S
H
G
K
T
Rat
Rattus norvegicus
Q9QX27
1032
113416
Y657
G
W
N
V
P
I
N
Y
S
K
S
H
G
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515322
1022
112674
K653
N
Y
S
K
T
H
A
K
K
E
E
E
K
E
K
Chicken
Gallus gallus
XP_419199
1093
120684
Y719
G
W
D
T
P
I
N
Y
S
K
T
H
G
R
K
Frog
Xenopus laevis
P70047
1122
123844
D715
S
Q
T
S
R
Q
D
D
W
D
G
P
I
D
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
42.3
90.7
N.A.
84.9
84.1
N.A.
78.1
75.9
46.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
58.2
93.3
N.A.
90.9
90.4
N.A.
86.1
84.3
63
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
80
80
N.A.
0
86.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
20
93.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
45
0
0
0
12
12
0
12
0
0
0
12
0
% D
% Glu:
0
0
12
0
0
12
12
0
0
12
12
12
12
12
0
% E
% Phe:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
67
0
0
0
0
0
0
0
0
0
12
12
67
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
67
0
0
0
% H
% Ile:
0
0
0
0
0
67
0
0
0
0
0
0
12
0
0
% I
% Lys:
0
0
0
12
0
0
0
12
12
67
0
0
12
56
23
% K
% Leu:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
23
0
0
0
67
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
67
0
0
0
0
0
12
12
0
0
0
% P
% Gln:
0
23
0
0
0
12
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
12
0
0
12
12
0
0
0
0
12
0
% R
% Ser:
12
0
12
12
0
0
0
0
67
0
23
0
0
0
0
% S
% Thr:
0
0
12
45
12
0
0
0
0
0
45
0
0
0
67
% T
% Val:
0
0
0
23
0
0
0
0
0
0
0
0
0
12
0
% V
% Trp:
0
67
0
0
0
0
0
0
12
0
0
0
0
0
0
% W
% Tyr:
0
12
0
0
0
0
0
67
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _