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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK1 All Species: 20.61
Human Site: S388 Identified Species: 34.87
UniProt: O60285 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60285 NP_055655.1 661 74305 S388 G Q D A V P E S P S K L S S K
Chimpanzee Pan troglodytes XP_001161041 661 74289 S388 S Q D A V P E S P S K L S S K
Rhesus Macaque Macaca mulatta XP_001098986 667 74748 S394 G L D A V P E S P S K L S S K
Dog Lupus familis XP_538417 666 74288 S393 G Q D P M P E S P N K L T S K
Cat Felis silvestris
Mouse Mus musculus Q641K5 658 73643 S389 G Q D S V P E S P S K L S S K
Rat Rattus norvegicus Q66HE5 630 69934 S367 Q H V P G G G S T G P G L E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508265 661 73136 S388 E G S A E S P S K S G S K R P
Chicken Gallus gallus Q9IA88 798 88848 T380 E M P Q D S L T S E T L R S S
Frog Xenopus laevis NP_001088596 570 64876 S307 V G G W L R R S S R P L W D N
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 H710 P P T H P S N H L F R P A N Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649991 1427 153426 N1011 A Q D T L N T N A N T S A S A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 G554 T G A S I T A G S A L A S A A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 L248 L S S E A R D L I P R M L I V
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 L367 K D E I Y E S L E S S E D T P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.9 91.7 N.A. 90.9 55.6 N.A. 84.2 26.1 48.5 23.5 N.A. 24.3 N.A. 22.4 N.A.
Protein Similarity: 100 99.8 98 94.4 N.A. 93.8 68 N.A. 88 42.8 61.4 36.2 N.A. 33.6 N.A. 35.8 N.A.
P-Site Identity: 100 93.3 93.3 73.3 N.A. 93.3 6.6 N.A. 20 13.3 13.3 0 N.A. 20 N.A. 6.6 N.A.
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 100 13.3 N.A. 20 20 20 26.6 N.A. 46.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.1 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 0 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 29 8 0 8 0 8 8 0 8 15 8 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 43 0 8 0 8 0 0 0 0 0 8 8 0 % D
% Glu: 15 0 8 8 8 8 36 0 8 8 0 8 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 29 22 8 0 8 8 8 8 0 8 8 8 0 0 0 % G
% His: 0 8 0 8 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 0 8 0 0 0 0 8 0 % I
% Lys: 8 0 0 0 0 0 0 0 8 0 36 0 8 0 36 % K
% Leu: 8 8 0 0 15 0 8 15 8 0 8 50 15 0 0 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 8 8 8 0 15 0 0 0 8 8 % N
% Pro: 8 8 8 15 8 36 8 0 36 8 15 8 0 0 15 % P
% Gln: 8 36 0 8 0 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 0 0 0 15 8 0 0 8 15 0 8 8 8 % R
% Ser: 8 8 15 15 0 22 8 58 22 43 8 15 36 50 8 % S
% Thr: 8 0 8 8 0 8 8 8 8 0 15 0 8 8 0 % T
% Val: 8 0 8 0 29 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _