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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
23.64
Human Site:
S481
Identified Species:
40
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S481
R
E
S
G
Y
Y
S
S
P
E
R
S
E
S
S
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S481
R
E
S
G
Y
Y
S
S
P
E
R
S
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S487
R
E
S
G
Y
Y
S
S
P
E
R
S
E
S
S
Dog
Lupus familis
XP_538417
666
74288
S486
R
E
S
G
Y
Y
S
S
P
E
R
S
E
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S482
R
E
S
G
Y
Y
S
S
P
E
R
S
E
S
S
Rat
Rattus norvegicus
Q66HE5
630
69934
R460
K
G
I
L
K
K
S
R
Q
R
E
S
G
Y
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
S481
R
E
S
G
Y
Y
S
S
P
E
R
S
E
S
S
Chicken
Gallus gallus
Q9IA88
798
88848
R473
I
P
S
N
T
S
R
R
H
T
L
A
E
V
T
Frog
Xenopus laevis
NP_001088596
570
64876
P400
Q
T
Q
N
N
E
L
P
P
S
P
L
T
S
S
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
Q803
V
E
L
G
G
G
A
Q
R
Q
S
F
L
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
A1104
P
V
A
D
L
R
S
A
P
P
R
E
G
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
N647
I
P
P
L
F
N
R
N
S
T
A
T
S
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
G341
N
R
F
R
V
P
S
G
Y
L
E
S
E
F
Q
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
Y460
Q
S
P
F
M
D
Q
Y
K
E
E
D
S
T
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
100
13.3
20
13.3
N.A.
20
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
100
26.6
26.6
40
N.A.
33.3
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
8
0
0
8
8
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
50
0
0
0
8
0
0
0
50
22
8
58
0
0
% E
% Phe:
0
0
8
8
8
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
8
0
50
8
8
0
8
0
0
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% H
% Ile:
15
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
8
8
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
0
8
15
8
0
8
0
0
8
8
8
8
0
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
15
8
8
0
8
0
0
0
0
0
0
0
% N
% Pro:
8
15
15
0
0
8
0
8
58
8
8
0
0
8
0
% P
% Gln:
15
0
8
0
0
0
8
8
8
8
0
0
0
0
8
% Q
% Arg:
43
8
0
8
0
8
15
15
8
8
50
0
0
0
0
% R
% Ser:
0
8
50
0
0
8
65
43
8
8
8
58
15
58
50
% S
% Thr:
0
8
0
0
8
0
0
0
0
15
0
8
8
8
15
% T
% Val:
8
8
0
0
8
0
0
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
43
43
0
8
8
0
0
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _