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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUAK1 All Species: 16.06
Human Site: S514 Identified Species: 27.18
UniProt: O60285 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60285 NP_055655.1 661 74305 S514 P D P A R V T S H S L S C R R
Chimpanzee Pan troglodytes XP_001161041 661 74289 S514 P D P A R V T S H S L S C R R
Rhesus Macaque Macaca mulatta XP_001098986 667 74748 S520 P D P A R V T S H S L S C R R
Dog Lupus familis XP_538417 666 74288 V519 P D P A R G P V L G L S C R R
Cat Felis silvestris
Mouse Mus musculus Q641K5 658 73643 S515 P D P A R G T S H S L S C R R
Rat Rattus norvegicus Q66HE5 630 69934 Q493 V S G D P M E Q K S P Q A S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508265 661 73136 S514 G G P T R L G S P S L A Y R R
Chicken Gallus gallus Q9IA88 798 88848 D506 P T E G T S S D S C L T S S S
Frog Xenopus laevis NP_001088596 570 64876 I433 P N A G R K G I L K R N G K F
Zebra Danio Brachydanio rerio Q6NSM8 1187 130949 H836 S R S L S R F H T S A Y E Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649991 1427 153426 Q1137 K E H V I T I Q R P P T Q H A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q9TW45 1192 126331 A680 R I P L N S T A V Q G H R T A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P92958 512 58671 A374 P V G H W I P A H V D H Y G L
Baker's Yeast Sacchar. cerevisiae P06782 633 72027 I493 G S P A A S K I S P L V T K K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.9 91.7 N.A. 90.9 55.6 N.A. 84.2 26.1 48.5 23.5 N.A. 24.3 N.A. 22.4 N.A.
Protein Similarity: 100 99.8 98 94.4 N.A. 93.8 68 N.A. 88 42.8 61.4 36.2 N.A. 33.6 N.A. 35.8 N.A.
P-Site Identity: 100 100 100 66.6 N.A. 93.3 6.6 N.A. 46.6 13.3 13.3 6.6 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 100 100 66.6 N.A. 93.3 13.3 N.A. 60 26.6 33.3 13.3 N.A. 13.3 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.1 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 43 8 0 0 15 0 0 8 8 8 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 36 0 0 % C
% Asp: 0 36 0 8 0 0 0 8 0 0 8 0 0 0 0 % D
% Glu: 0 8 8 0 0 0 8 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % F
% Gly: 15 8 15 15 0 15 15 0 0 8 8 0 8 8 8 % G
% His: 0 0 8 8 0 0 0 8 36 0 0 15 0 8 0 % H
% Ile: 0 8 0 0 8 8 8 15 0 0 0 0 0 0 0 % I
% Lys: 8 0 0 0 0 8 8 0 8 8 0 0 0 15 8 % K
% Leu: 0 0 0 15 0 8 0 0 15 0 58 0 0 0 15 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 0 0 0 0 8 0 0 0 % N
% Pro: 58 0 58 0 8 0 15 0 8 15 15 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 15 0 8 0 8 8 8 0 % Q
% Arg: 8 8 0 0 50 8 0 0 8 0 8 0 8 43 43 % R
% Ser: 8 15 8 0 8 22 8 36 15 50 0 36 8 15 8 % S
% Thr: 0 8 0 8 8 8 36 0 8 0 0 15 8 8 0 % T
% Val: 8 8 0 8 0 22 0 8 8 8 0 8 0 0 0 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 15 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _