KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
11.82
Human Site:
T356
Identified Species:
20
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
T356
M
K
G
L
A
K
P
T
T
S
E
V
M
L
E
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
T356
M
K
G
L
A
K
P
T
T
S
E
V
M
L
E
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
T362
M
K
G
L
V
K
P
T
T
S
E
V
M
L
E
Dog
Lupus familis
XP_538417
666
74288
G361
I
K
G
L
A
K
P
G
A
S
E
V
M
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
G357
M
K
G
L
A
K
P
G
A
S
E
V
V
L
E
Rat
Rattus norvegicus
Q66HE5
630
69934
S335
S
G
D
S
G
R
A
S
M
A
D
W
L
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
S356
G
L
A
K
A
G
S
S
E
A
P
L
E
R
Q
Chicken
Gallus gallus
Q9IA88
798
88848
R348
L
E
R
L
K
E
Y
R
S
S
Q
L
S
S
R
Frog
Xenopus laevis
NP_001088596
570
64876
W275
A
D
V
A
S
H
W
W
V
N
W
G
Y
T
Q
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
G678
Q
I
Q
A
L
S
L
G
H
G
E
N
Q
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
I979
S
R
C
N
S
S
N
I
G
N
C
N
T
M
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
E522
P
A
G
V
I
T
R
E
H
V
T
S
S
S
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
L216
Y
A
L
L
C
G
T
L
P
F
D
D
E
N
I
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
D335
E
N
N
D
S
K
K
D
G
S
S
P
D
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
93.3
80
N.A.
80
0
N.A.
6.6
13.3
0
6.6
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
33.3
N.A.
33.3
53.3
20
6.6
N.A.
26.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
15
36
0
8
0
15
15
0
0
0
0
8
% A
% Cys:
0
0
8
0
8
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
0
8
8
8
0
0
0
8
0
0
15
8
8
0
8
% D
% Glu:
8
8
0
0
0
8
0
8
8
0
43
0
15
0
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% F
% Gly:
8
8
43
0
8
15
0
22
15
8
0
8
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
15
0
0
0
0
0
0
% H
% Ile:
8
8
0
0
8
0
0
8
0
0
0
0
0
0
8
% I
% Lys:
0
36
0
8
8
43
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
50
8
0
8
8
0
0
0
15
8
36
0
% L
% Met:
29
0
0
0
0
0
0
0
8
0
0
0
29
8
0
% M
% Asn:
0
8
8
8
0
0
8
0
0
15
0
15
0
15
0
% N
% Pro:
8
0
0
0
0
0
36
0
8
0
8
8
0
8
8
% P
% Gln:
8
0
8
0
0
0
0
0
0
0
8
0
8
0
15
% Q
% Arg:
0
8
8
0
0
8
8
8
0
0
0
0
0
15
15
% R
% Ser:
15
0
0
8
22
15
8
15
8
50
8
8
15
15
8
% S
% Thr:
0
0
0
0
0
8
8
22
22
0
8
0
8
8
0
% T
% Val:
0
0
8
8
8
0
0
0
8
8
0
36
8
0
0
% V
% Trp:
0
0
0
0
0
0
8
8
0
0
8
8
0
0
0
% W
% Tyr:
8
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _