KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGRN1
All Species:
19.09
Human Site:
S379
Identified Species:
35
UniProt:
O60291
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60291
NP_001135761.1
552
60753
S379
K
P
K
R
E
T
N
S
D
S
V
P
P
G
Y
Chimpanzee
Pan troglodytes
XP_510786
756
82503
S559
K
P
K
R
E
T
N
S
D
S
I
P
P
G
Y
Rhesus Macaque
Macaca mulatta
XP_001097963
797
86206
T495
E
A
L
N
G
P
L
T
P
S
P
A
V
P
P
Dog
Lupus familis
XP_536988
551
60389
S353
K
P
K
R
E
T
S
S
D
S
V
P
P
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9D074
532
58459
S357
D
H
D
E
H
S
S
S
D
S
I
P
P
G
Y
Rat
Rattus norvegicus
Q5XIQ4
533
58584
S358
D
H
D
E
H
S
N
S
D
S
V
P
P
G
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516608
503
55648
E335
D
N
I
P
P
G
Y
E
P
I
S
L
L
E
A
Chicken
Gallus gallus
XP_414957
536
59384
S359
G
L
R
S
V
S
P
S
I
P
S
A
P
L
Y
Frog
Xenopus laevis
Q6INH1
674
73240
S379
L
N
G
P
L
T
P
S
P
S
A
P
P
L
R
Zebra Danio
Brachydanio rerio
Q7ZUL9
529
58127
A356
D
H
T
E
H
S
N
A
D
N
I
P
P
G
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572915
789
83843
D547
D
G
S
A
G
T
D
D
D
V
D
S
E
N
E
Honey Bee
Apis mellifera
XP_624563
555
61792
E385
R
T
T
V
L
A
P
E
T
P
D
T
P
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781055
450
49149
A282
I
C
R
A
P
F
R
A
L
L
Q
I
R
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
40.4
85.1
N.A.
87.1
86.9
N.A.
78.4
67.5
47
68.3
N.A.
31.9
39.2
N.A.
40.5
Protein Similarity:
100
70.2
50.3
90.2
N.A.
91.3
91.3
N.A.
84.4
77.3
59.2
77.7
N.A.
45.1
54.9
N.A.
55.2
P-Site Identity:
100
93.3
6.6
93.3
N.A.
46.6
60
N.A.
0
20
33.3
40
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
66.6
66.6
N.A.
0
33.3
33.3
66.6
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
0
8
0
16
0
0
8
16
0
8
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
39
0
16
0
0
0
8
8
54
0
16
0
0
8
0
% D
% Glu:
8
0
0
24
24
0
0
16
0
0
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
8
0
16
8
0
0
0
0
0
0
0
47
0
% G
% His:
0
24
0
0
24
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
8
8
24
8
0
0
0
% I
% Lys:
24
0
24
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
8
8
0
16
0
8
0
8
8
0
8
8
16
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
0
8
0
0
31
0
0
8
0
0
0
8
0
% N
% Pro:
0
24
0
16
16
8
24
0
24
16
8
54
70
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Q
% Arg:
8
0
16
24
0
0
8
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
8
8
0
31
16
54
0
54
16
8
0
0
0
% S
% Thr:
0
8
16
0
0
39
0
8
8
0
0
8
0
0
8
% T
% Val:
0
0
0
8
8
0
0
0
0
8
24
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
54
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _