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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGRN1
All Species:
20.91
Human Site:
S453
Identified Species:
38.33
UniProt:
O60291
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60291
NP_001135761.1
552
60753
S453
P
Q
S
K
A
P
D
S
T
L
R
S
P
S
S
Chimpanzee
Pan troglodytes
XP_510786
756
82503
S633
P
Q
S
K
A
P
D
S
T
L
R
S
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001097963
797
86206
S569
H
E
E
E
D
E
R
S
C
S
E
S
E
T
Q
Dog
Lupus familis
XP_536988
551
60389
S427
P
R
S
R
S
P
D
S
T
L
R
S
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9D074
532
58459
S431
T
Q
S
K
S
P
D
S
T
L
R
S
P
S
F
Rat
Rattus norvegicus
Q5XIQ4
533
58584
S432
T
Q
S
K
S
P
D
S
T
L
R
S
P
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516608
503
55648
I409
L
R
S
P
S
S
P
I
H
E
E
D
E
E
K
Chicken
Gallus gallus
XP_414957
536
59384
A433
E
D
S
D
S
Q
P
A
L
G
G
G
E
L
V
Frog
Xenopus laevis
Q6INH1
674
73240
Q453
S
F
S
E
A
E
I
Q
T
P
R
K
K
T
S
Zebra Danio
Brachydanio rerio
Q7ZUL9
529
58127
P430
P
D
G
S
V
R
S
P
S
S
P
I
Q
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572915
789
83843
S621
P
R
P
E
L
S
G
S
G
A
P
S
P
A
E
Honey Bee
Apis mellifera
XP_624563
555
61792
N459
G
S
Q
K
D
V
H
N
R
S
P
A
M
R
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781055
450
49149
K356
G
T
S
E
G
R
R
K
K
K
K
S
R
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
40.4
85.1
N.A.
87.1
86.9
N.A.
78.4
67.5
47
68.3
N.A.
31.9
39.2
N.A.
40.5
Protein Similarity:
100
70.2
50.3
90.2
N.A.
91.3
91.3
N.A.
84.4
77.3
59.2
77.7
N.A.
45.1
54.9
N.A.
55.2
P-Site Identity:
100
100
13.3
80
N.A.
80
86.6
N.A.
6.6
6.6
33.3
6.6
N.A.
26.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
33.3
100
N.A.
86.6
93.3
N.A.
20
20
46.6
13.3
N.A.
46.6
20
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
24
0
0
8
0
8
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% C
% Asp:
0
16
0
8
16
0
39
0
0
0
0
8
0
0
0
% D
% Glu:
8
8
8
31
0
16
0
0
0
8
16
0
24
16
16
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
16
0
8
0
8
0
8
0
8
8
8
8
0
0
0
% G
% His:
8
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
8
% I
% Lys:
0
0
0
39
0
0
0
8
8
8
8
8
8
0
8
% K
% Leu:
8
0
0
0
8
0
0
0
8
39
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
39
0
8
8
0
39
16
8
0
8
24
0
47
0
0
% P
% Gln:
0
31
8
0
0
8
0
8
0
0
0
0
8
0
8
% Q
% Arg:
0
24
0
8
0
16
16
0
8
0
47
0
8
8
0
% R
% Ser:
8
8
70
8
39
16
8
54
8
24
0
62
0
39
39
% S
% Thr:
16
8
0
0
0
0
0
0
47
0
0
0
0
24
0
% T
% Val:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _