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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGRN1
All Species:
17.27
Human Site:
S490
Identified Species:
31.67
UniProt:
O60291
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60291
NP_001135761.1
552
60753
S490
A
E
L
A
L
R
E
S
S
S
P
E
S
F
I
Chimpanzee
Pan troglodytes
XP_510786
756
82503
S670
A
E
L
A
L
R
E
S
S
S
P
E
S
F
I
Rhesus Macaque
Macaca mulatta
XP_001097963
797
86206
N693
P
A
E
S
P
D
S
N
F
A
G
L
P
A
G
Dog
Lupus familis
XP_536988
551
60389
S462
S
G
V
G
L
A
L
S
S
S
P
E
S
F
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D074
532
58459
S468
V
E
L
V
L
R
E
S
S
S
P
E
S
F
G
Rat
Rattus norvegicus
Q5XIQ4
533
58584
S469
V
E
L
V
L
Q
E
S
S
S
P
E
S
F
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516608
503
55648
S442
R
E
S
S
S
P
E
S
I
V
T
E
E
I
E
Chicken
Gallus gallus
XP_414957
536
59384
S469
Q
K
S
G
C
P
P
S
V
E
D
V
L
Q
D
Frog
Xenopus laevis
Q6INH1
674
73240
A556
I
T
P
S
P
P
A
A
A
S
G
S
P
S
I
Zebra Danio
Brachydanio rerio
Q7ZUL9
529
58127
G468
P
S
E
D
T
V
E
G
V
T
A
K
P
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572915
789
83843
K725
V
T
T
V
V
D
L
K
S
N
N
V
S
S
L
Honey Bee
Apis mellifera
XP_624563
555
61792
V493
L
V
N
E
K
Q
P
V
S
L
Y
E
G
Q
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781055
450
49149
V389
Q
A
N
S
Y
Q
E
V
N
E
K
N
E
M
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
40.4
85.1
N.A.
87.1
86.9
N.A.
78.4
67.5
47
68.3
N.A.
31.9
39.2
N.A.
40.5
Protein Similarity:
100
70.2
50.3
90.2
N.A.
91.3
91.3
N.A.
84.4
77.3
59.2
77.7
N.A.
45.1
54.9
N.A.
55.2
P-Site Identity:
100
100
0
53.3
N.A.
80
73.3
N.A.
26.6
6.6
13.3
6.6
N.A.
13.3
13.3
N.A.
6.6
P-Site Similarity:
100
100
20
73.3
N.A.
80
80
N.A.
33.3
13.3
33.3
26.6
N.A.
33.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
16
0
16
0
8
8
8
8
8
8
0
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
16
0
0
0
0
8
0
0
0
8
% D
% Glu:
0
39
16
8
0
0
54
0
0
16
0
54
16
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
39
0
% F
% Gly:
0
8
0
16
0
0
0
8
0
0
16
0
8
8
31
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
24
% I
% Lys:
0
8
0
0
8
0
0
8
0
0
8
8
0
0
0
% K
% Leu:
8
0
31
0
39
0
16
0
0
8
0
8
8
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
16
0
0
0
0
8
8
8
8
8
0
0
0
% N
% Pro:
16
0
8
0
16
24
16
0
0
0
39
0
24
0
0
% P
% Gln:
16
0
0
0
0
24
0
0
0
0
0
0
0
16
0
% Q
% Arg:
8
0
0
0
0
24
0
0
0
0
0
0
0
0
0
% R
% Ser:
8
8
16
31
8
0
8
54
54
47
0
8
47
16
0
% S
% Thr:
0
16
8
0
8
0
0
0
0
8
8
0
0
0
0
% T
% Val:
24
8
8
24
8
8
0
16
16
8
0
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _