KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MGRN1
All Species:
26.06
Human Site:
Y386
Identified Species:
47.78
UniProt:
O60291
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60291
NP_001135761.1
552
60753
Y386
S
D
S
V
P
P
G
Y
E
P
I
S
L
L
E
Chimpanzee
Pan troglodytes
XP_510786
756
82503
Y566
S
D
S
I
P
P
G
Y
E
P
I
S
L
L
E
Rhesus Macaque
Macaca mulatta
XP_001097963
797
86206
P502
T
P
S
P
A
V
P
P
L
H
V
L
G
D
G
Dog
Lupus familis
XP_536988
551
60389
Y360
S
D
S
V
P
P
G
Y
E
P
I
S
L
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9D074
532
58459
Y364
S
D
S
I
P
P
G
Y
E
P
I
S
L
L
E
Rat
Rattus norvegicus
Q5XIQ4
533
58584
Y365
S
D
S
V
P
P
G
Y
E
P
I
S
L
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516608
503
55648
A342
E
P
I
S
L
L
E
A
L
N
G
L
R
S
I
Chicken
Gallus gallus
XP_414957
536
59384
Y366
S
I
P
S
A
P
L
Y
D
E
I
N
Y
S
G
Frog
Xenopus laevis
Q6INH1
674
73240
R386
S
P
S
A
P
P
L
R
A
L
G
E
A
R
R
Zebra Danio
Brachydanio rerio
Q7ZUL9
529
58127
Y363
A
D
N
I
P
P
G
Y
E
P
I
S
L
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572915
789
83843
E554
D
D
V
D
S
E
N
E
K
L
S
P
L
L
S
Honey Bee
Apis mellifera
XP_624563
555
61792
T392
E
T
P
D
T
P
D
T
D
T
A
S
A
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781055
450
49149
L289
A
L
L
Q
I
R
A
L
R
K
V
M
G
N
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.1
40.4
85.1
N.A.
87.1
86.9
N.A.
78.4
67.5
47
68.3
N.A.
31.9
39.2
N.A.
40.5
Protein Similarity:
100
70.2
50.3
90.2
N.A.
91.3
91.3
N.A.
84.4
77.3
59.2
77.7
N.A.
45.1
54.9
N.A.
55.2
P-Site Identity:
100
93.3
6.6
100
N.A.
93.3
100
N.A.
0
26.6
26.6
80
N.A.
20
13.3
N.A.
0
P-Site Similarity:
100
100
20
100
N.A.
100
100
N.A.
0
40
26.6
100
N.A.
26.6
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
8
16
0
8
8
8
0
8
0
16
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
54
0
16
0
0
8
0
16
0
0
0
0
8
0
% D
% Glu:
16
0
0
0
0
8
8
8
47
8
0
8
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
47
0
0
0
16
0
16
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
8
24
8
0
0
0
0
0
54
0
0
8
8
% I
% Lys:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% K
% Leu:
0
8
8
0
8
8
16
8
16
16
0
16
54
54
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
8
0
8
0
8
0
% N
% Pro:
0
24
16
8
54
70
8
8
0
47
0
8
0
0
8
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
8
8
0
0
0
8
8
8
% R
% Ser:
54
0
54
16
8
0
0
0
0
0
8
54
0
16
8
% S
% Thr:
8
8
0
0
8
0
0
8
0
8
0
0
0
0
0
% T
% Val:
0
0
8
24
0
8
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
54
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _