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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFC3H1 All Species: 21.52
Human Site: S575 Identified Species: 67.62
UniProt: O60293 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60293 NP_659419.3 1989 226356 S575 L P P P P Q V S S L P P L S Q
Chimpanzee Pan troglodytes XP_509222 1989 226351 S575 L P P P P Q V S S L P P L S Q
Rhesus Macaque Macaca mulatta XP_001117507 1989 226341 S575 L P P P P Q V S S L P P L S Q
Dog Lupus familis XP_531679 1993 224865 S658 L P P P P Q V S S M P P L S Q
Cat Felis silvestris
Mouse Mus musculus NP_001028433 1992 225035 S578 L P P P A Q V S S V P S L N Q
Rat Rattus norvegicus XP_001078700 1994 225353 S580 L P P P A Q V S S V P S L S Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520915 899 101298
Chicken Gallus gallus XP_416097 2076 236173 I664 S L P L P P P I P P L P S L S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.1 90.2 N.A. 91.5 91.8 N.A. 33.4 70.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.9 99.7 92.7 N.A. 95.3 95.3 N.A. 38.9 81.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 73.3 80 N.A. 0 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 0 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 75 13 0 13 0 0 0 0 0 38 13 0 75 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % N
% Pro: 0 75 88 75 63 13 13 0 13 13 75 63 0 0 0 % P
% Gln: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 75 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 0 0 0 0 0 0 75 75 0 0 25 13 63 13 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 75 0 0 25 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _