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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCMT2 All Species: 23.64
Human Site: S362 Identified Species: 57.78
UniProt: O60294 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60294 NP_055608.2 686 75602 S362 L K R Y G H A S V F L S P D V
Chimpanzee Pan troglodytes XP_001157403 686 75594 S362 L K R Y G H A S V F L S P D V
Rhesus Macaque Macaca mulatta XP_001106399 705 77724 S362 L K R Y G H A S V L L S P D V
Dog Lupus familis XP_544648 687 75289 S362 L K R Y G H A S V L L S P S I
Cat Felis silvestris
Mouse Mus musculus Q8BYR1 686 75245 S362 L K R Y G H A S A L L S P G V
Rat Rattus norvegicus Q5XIA3 686 75514 S362 L Q R Y G H T S V L L S P G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417263 744 82265 S420 L R R Y G H H S S V I K P N V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122029 673 74152 M349 P P L V V Q P M C G S P S V E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792604 724 79488 S401 A T W L R L F S H A S V L L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08282 695 78956 L371 R S I S E I N L T V D E D Y Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.1 82.9 N.A. 77.9 77.2 N.A. N.A. 47.8 N.A. 46 N.A. N.A. N.A. N.A. 40.1
Protein Similarity: 100 99.8 94.8 89.6 N.A. 86.1 85.2 N.A. N.A. 62.2 N.A. 62.9 N.A. N.A. N.A. N.A. 57.6
P-Site Identity: 100 100 93.3 80 N.A. 80 66.6 N.A. N.A. 53.3 N.A. 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 93.3 86.6 N.A. 80 80 N.A. N.A. 73.3 N.A. 0 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 50 0 10 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 0 10 30 0 % D
% Glu: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 20 0 0 0 0 0 % F
% Gly: 0 0 0 0 70 0 0 0 0 10 0 0 0 20 0 % G
% His: 0 0 0 0 0 70 10 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 10 0 0 0 0 10 0 0 0 20 % I
% Lys: 0 50 0 0 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 70 0 10 10 0 10 0 10 0 40 60 0 10 10 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 10 0 % N
% Pro: 10 10 0 0 0 0 10 0 0 0 0 10 70 0 0 % P
% Gln: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 10 % Q
% Arg: 10 10 70 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 10 0 10 0 0 0 80 10 0 20 60 10 10 0 % S
% Thr: 0 10 0 0 0 0 10 0 10 0 0 0 0 0 0 % T
% Val: 0 0 0 10 10 0 0 0 50 20 0 10 0 10 50 % V
% Trp: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 70 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _