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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCMT2 All Species: 22.73
Human Site: S387 Identified Species: 55.56
UniProt: O60294 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60294 NP_055608.2 686 75602 S387 E G R H C R V S Q F H L L S R
Chimpanzee Pan troglodytes XP_001157403 686 75594 S387 E G R H C R V S Q F H L L S R
Rhesus Macaque Macaca mulatta XP_001106399 705 77724 S387 E G R H C R V S Q F H L L S R
Dog Lupus familis XP_544648 687 75289 S387 E G R H C R V S K F H L L S R
Cat Felis silvestris
Mouse Mus musculus Q8BYR1 686 75245 S387 E G R H C R V S R F H V L S R
Rat Rattus norvegicus Q5XIA3 686 75514 S387 E G R H C R V S R F H L L S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417263 744 82265 R445 N G H H C R M R N F H V L I K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122029 673 74152 G374 P E I I L L T G G F G R N G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792604 724 79488 H426 F G D S E G C H G R M E K V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08282 695 78956 A396 K F G D V D V A G N D V F Y M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.1 82.9 N.A. 77.9 77.2 N.A. N.A. 47.8 N.A. 46 N.A. N.A. N.A. N.A. 40.1
Protein Similarity: 100 99.8 94.8 89.6 N.A. 86.1 85.2 N.A. N.A. 62.2 N.A. 62.9 N.A. N.A. N.A. N.A. 57.6
P-Site Identity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. N.A. 46.6 N.A. 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 66.6 N.A. 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 70 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 10 0 0 0 0 10 0 0 0 0 % D
% Glu: 60 10 0 0 10 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 10 10 0 0 0 0 0 0 0 80 0 0 10 0 0 % F
% Gly: 0 80 10 0 0 10 0 10 30 0 10 0 0 10 0 % G
% His: 0 0 10 70 0 0 0 10 0 0 70 0 0 0 0 % H
% Ile: 0 0 10 10 0 0 0 0 0 0 0 0 0 10 0 % I
% Lys: 10 0 0 0 0 0 0 0 10 0 0 0 10 0 10 % K
% Leu: 0 0 0 0 10 10 0 0 0 0 0 50 70 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 10 0 0 0 10 % M
% Asn: 10 0 0 0 0 0 0 0 10 10 0 0 10 0 0 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 30 0 0 0 0 0 10 % Q
% Arg: 0 0 60 0 0 70 0 10 20 10 0 10 0 0 70 % R
% Ser: 0 0 0 10 0 0 0 60 0 0 0 0 0 60 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 10 0 70 0 0 0 0 30 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _