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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LCMT2
All Species:
8.48
Human Site:
S403
Identified Species:
20.74
UniProt:
O60294
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60294
NP_055608.2
686
75602
S403
C
D
S
E
W
K
G
S
Q
I
G
S
C
G
T
Chimpanzee
Pan troglodytes
XP_001157403
686
75594
S403
C
D
S
E
W
K
G
S
Q
I
G
S
C
G
T
Rhesus Macaque
Macaca mulatta
XP_001106399
705
77724
S403
G
D
S
E
W
K
G
S
Q
I
G
D
C
G
T
Dog
Lupus familis
XP_544648
687
75289
N403
C
D
F
E
W
K
G
N
Q
I
C
S
C
G
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR1
686
75245
C403
C
D
S
E
W
E
G
C
Q
I
S
T
L
G
T
Rat
Rattus norvegicus
Q5XIA3
686
75514
C403
C
D
S
E
W
K
G
C
Q
I
S
T
L
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417263
744
82265
C461
A
G
S
W
K
T
K
C
V
K
K
E
N
P
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122029
673
74152
K390
T
A
A
R
V
L
I
K
E
K
C
G
W
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_792604
724
79488
I442
V
N
L
D
L
G
T
I
E
E
L
D
A
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08282
695
78956
N412
G
S
N
P
Y
R
V
N
E
I
L
Q
M
S
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
93.1
82.9
N.A.
77.9
77.2
N.A.
N.A.
47.8
N.A.
46
N.A.
N.A.
N.A.
N.A.
40.1
Protein Similarity:
100
99.8
94.8
89.6
N.A.
86.1
85.2
N.A.
N.A.
62.2
N.A.
62.9
N.A.
N.A.
N.A.
N.A.
57.6
P-Site Identity:
100
100
86.6
80
N.A.
66.6
73.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
86.6
N.A.
80
80
N.A.
N.A.
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
0
0
0
0
0
0
10
10
0
% A
% Cys:
50
0
0
0
0
0
0
30
0
0
20
0
40
0
0
% C
% Asp:
0
60
0
10
0
0
0
0
0
0
0
20
0
0
10
% D
% Glu:
0
0
0
60
0
10
0
0
30
10
0
10
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
10
0
0
0
10
60
0
0
0
30
10
0
60
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
10
0
70
0
0
0
0
10
% I
% Lys:
0
0
0
0
10
50
10
10
0
20
10
0
0
10
0
% K
% Leu:
0
0
10
0
10
10
0
0
0
0
20
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
10
0
0
0
0
20
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
60
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
60
0
0
0
0
30
0
0
20
30
0
10
10
% S
% Thr:
10
0
0
0
0
10
10
0
0
0
0
20
0
0
60
% T
% Val:
10
0
0
0
10
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
60
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _