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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCMT2 All Species: 21.52
Human Site: T584 Identified Species: 52.59
UniProt: O60294 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60294 NP_055608.2 686 75602 T584 V D I Q P P I T P R Y S H T A
Chimpanzee Pan troglodytes XP_001157403 686 75594 T584 V D I Q P P I T P R Y S H T A
Rhesus Macaque Macaca mulatta XP_001106399 705 77724 T584 I D I Q P P I T P R Y S H T A
Dog Lupus familis XP_544648 687 75289 T583 I V I Q P P I T P R Y S H T A
Cat Felis silvestris
Mouse Mus musculus Q8BYR1 686 75245 T584 I D I Q P S I T P R Y S H T A
Rat Rattus norvegicus Q5XIA3 686 75514 T584 I H I Q P S I T P R Y S H T A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417263 744 82265 I642 I E T H P P L I P R Y S H T A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122029 673 74152 V571 K D L H P P P V P R Y S H S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792604 724 79488 K622 I E T I P P F K P R Y S H T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q08282 695 78956 P593 V I K K L Q H P L F Q R Y G S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 93.1 82.9 N.A. 77.9 77.2 N.A. N.A. 47.8 N.A. 46 N.A. N.A. N.A. N.A. 40.1
Protein Similarity: 100 99.8 94.8 89.6 N.A. 86.1 85.2 N.A. N.A. 62.2 N.A. 62.9 N.A. N.A. N.A. N.A. 57.6
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 80 N.A. N.A. 60 N.A. 60 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. N.A. 80 N.A. 73.3 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 90 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 20 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % G
% His: 0 10 0 20 0 0 10 0 0 0 0 0 90 0 0 % H
% Ile: 60 10 60 10 0 0 60 10 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 10 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 0 10 0 10 0 10 0 10 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 90 70 10 10 90 0 0 0 0 0 0 % P
% Gln: 0 0 0 60 0 10 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 90 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 20 0 0 0 0 0 90 0 10 10 % S
% Thr: 0 0 20 0 0 0 0 60 0 0 0 0 0 80 0 % T
% Val: 30 10 0 0 0 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 90 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _