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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPA1 All Species: 35.45
Human Site: T652 Identified Species: 78
UniProt: O60313 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60313 NP_056375.2 960 111631 T652 N S G T F N T T V D I K L K Q
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001087037 1092 125633 T784 N S G T F N T T V D I K L K Q
Dog Lupus familis XP_534321 1175 133763 T867 N S G T F N T T V D I K L K Q
Cat Felis silvestris
Mouse Mus musculus P58281 960 111321 T652 N S G T F N T T V D I K L K Q
Rat Rattus norvegicus Q2TA68 960 111289 T652 N S G T F N T T V D I K L K Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F499 977 113427 T669 N S G T F N T T V D I K L K Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5U3A7 966 111315 T658 N S G T F N T T V D I K L K Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610941 933 107185 M624 S Q N S F N T M V D I K L R Q
Honey Bee Apis mellifera XP_396882 918 106720 T610 S P S T F N T T V D I K L R Q
Nematode Worm Caenorhab. elegans NP_495986 964 110236 T651 S S G S F N T T V D I K L K H
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32266 881 99159 R621 L T K M G I G R L S T M L T T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.4 79.5 N.A. 96.3 95.9 N.A. N.A. 85.6 N.A. 79 N.A. 52.1 55 50.9 N.A.
Protein Similarity: 100 N.A. 87.6 80.5 N.A. 97.9 97.8 N.A. N.A. 92.3 N.A. 88.8 N.A. 69 73.9 69.2 N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 60 73.3 80 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 100 N.A. 100 N.A. 80 86.6 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 91 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 91 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 73 0 10 0 10 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 91 0 0 0 0 % I
% Lys: 0 0 10 0 0 0 0 0 0 0 0 91 0 73 0 % K
% Leu: 10 0 0 0 0 0 0 0 10 0 0 0 100 0 0 % L
% Met: 0 0 0 10 0 0 0 10 0 0 0 10 0 0 0 % M
% Asn: 64 0 10 0 0 91 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 82 % Q
% Arg: 0 0 0 0 0 0 0 10 0 0 0 0 0 19 0 % R
% Ser: 28 73 10 19 0 0 0 0 0 10 0 0 0 0 0 % S
% Thr: 0 10 0 73 0 0 91 82 0 0 10 0 0 10 10 % T
% Val: 0 0 0 0 0 0 0 0 91 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _