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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OPA1
All Species:
26.67
Human Site:
Y229
Identified Species:
58.67
UniProt:
O60313
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60313
NP_056375.2
960
111631
Y229
L
L
H
T
Q
L
K
Y
Q
R
I
L
E
R
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087037
1092
125633
Y361
L
L
H
T
Q
L
K
Y
Q
R
I
L
E
R
L
Dog
Lupus familis
XP_534321
1175
133763
Y444
L
L
H
T
Q
L
K
Y
Q
R
I
L
E
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P58281
960
111321
Y229
L
L
H
T
Q
L
K
Y
Q
R
I
L
E
R
L
Rat
Rattus norvegicus
Q2TA68
960
111289
Y229
L
L
H
T
Q
L
K
Y
Q
R
I
L
E
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F499
977
113427
Y246
L
L
R
T
Q
L
K
Y
Q
R
M
L
E
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U3A7
966
111315
Y235
L
L
R
T
Q
L
K
Y
Q
R
M
L
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610941
933
107185
I220
E
L
R
Q
Q
Y
L
I
L
K
T
N
K
K
T
Honey Bee
Apis mellifera
XP_396882
918
106720
K220
M
S
N
K
K
I
K
K
S
L
I
D
M
Y
S
Nematode Worm
Caenorhab. elegans
NP_495986
964
110236
K236
R
E
L
E
R
L
E
K
E
N
K
V
L
K
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32266
881
99159
E228
S
G
K
S
S
V
L
E
S
I
V
G
R
E
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.4
79.5
N.A.
96.3
95.9
N.A.
N.A.
85.6
N.A.
79
N.A.
52.1
55
50.9
N.A.
Protein Similarity:
100
N.A.
87.6
80.5
N.A.
97.9
97.8
N.A.
N.A.
92.3
N.A.
88.8
N.A.
69
73.9
69.2
N.A.
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
86.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
93.3
N.A.
93.3
N.A.
33.3
40
40
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
10
10
0
10
0
0
10
10
10
0
0
0
64
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
0
0
46
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
0
10
55
0
0
0
0
% I
% Lys:
0
0
10
10
10
0
73
19
0
10
10
0
10
19
0
% K
% Leu:
64
73
10
0
0
73
19
0
10
10
0
64
10
0
64
% L
% Met:
10
0
0
0
0
0
0
0
0
0
19
0
10
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
73
0
0
0
64
0
0
0
0
0
10
% Q
% Arg:
10
0
28
0
10
0
0
0
0
64
0
0
10
64
0
% R
% Ser:
10
10
0
10
10
0
0
0
19
0
0
0
0
0
10
% S
% Thr:
0
0
0
64
0
0
0
0
0
0
10
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
64
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _