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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3AP
All Species:
13.94
Human Site:
S422
Identified Species:
30.67
UniProt:
O60318
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60318
NP_003897.2
1980
218405
S422
R
Q
S
N
R
S
E
S
T
D
S
L
G
G
L
Chimpanzee
Pan troglodytes
XP_525497
1981
218320
S422
R
Q
S
N
R
S
E
S
T
D
S
L
G
G
L
Rhesus Macaque
Macaca mulatta
XP_001118009
1415
157213
T23
K
E
D
S
L
R
G
T
P
A
R
P
S
N
R
Dog
Lupus familis
XP_537925
1989
218752
S422
R
Q
S
K
R
S
E
S
T
D
S
L
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU9
1971
217122
W416
Q
S
K
R
R
E
E
W
I
Y
S
L
G
G
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514089
1519
168947
E126
N
L
A
G
A
A
A
E
T
A
E
E
R
Y
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689234
2082
230356
S468
R
R
A
A
R
K
E
S
T
D
S
L
G
G
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U3V9
1370
158161
Honey Bee
Apis mellifera
XP_395462
961
111706
Nematode Worm
Caenorhab. elegans
NP_501328
1116
129063
Sea Urchin
Strong. purpuratus
XP_795787
1945
218422
R453
K
K
A
T
V
N
P
R
K
T
M
A
T
V
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
69.1
83.7
N.A.
78.4
N.A.
N.A.
53.8
N.A.
N.A.
42.2
N.A.
21.3
20.6
21.3
25.4
Protein Similarity:
100
99.6
70.1
89.4
N.A.
85.5
N.A.
N.A.
62.7
N.A.
N.A.
58.5
N.A.
35.7
34.3
35.9
43
P-Site Identity:
100
100
0
93.3
N.A.
40
N.A.
N.A.
6.6
N.A.
N.A.
73.3
N.A.
0
0
0
0
P-Site Similarity:
100
100
26.6
93.3
N.A.
53.3
N.A.
N.A.
20
N.A.
N.A.
86.6
N.A.
0
0
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
28
10
10
10
10
0
0
19
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
0
0
0
0
0
0
37
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
10
46
10
0
0
10
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
0
0
46
46
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
19
10
10
10
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
10
0
0
0
0
0
0
46
0
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
10
0
0
19
0
10
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
10
0
10
0
0
10
0
0
0
% P
% Gln:
10
28
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
37
10
0
10
46
10
0
10
0
0
10
0
10
0
19
% R
% Ser:
0
10
28
10
0
28
0
37
0
0
46
0
10
0
0
% S
% Thr:
0
0
0
10
0
0
0
10
46
10
0
0
10
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _