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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MCM3AP
All Species:
5.15
Human Site:
S493
Identified Species:
11.33
UniProt:
O60318
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60318
NP_003897.2
1980
218405
S493
L
A
R
K
K
G
K
S
L
H
K
D
M
A
I
Chimpanzee
Pan troglodytes
XP_525497
1981
218320
S493
L
A
R
K
K
G
K
S
L
H
K
D
M
A
I
Rhesus Macaque
Macaca mulatta
XP_001118009
1415
157213
H92
A
V
V
H
F
F
D
H
A
S
A
A
L
A
R
Dog
Lupus familis
XP_537925
1989
218752
G493
L
A
R
K
K
G
K
G
L
H
K
D
M
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUU9
1971
217122
K486
A
L
A
R
K
K
G
K
G
L
H
K
D
V
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514089
1519
168947
S195
G
T
D
Q
V
D
H
S
A
A
I
K
E
Y
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689234
2082
230356
Q541
K
K
K
G
K
L
F
Q
R
N
E
I
Q
I
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9U3V9
1370
158161
P46
L
V
N
F
V
L
R
P
R
R
M
T
C
T
V
Honey Bee
Apis mellifera
XP_395462
961
111706
Nematode Worm
Caenorhab. elegans
NP_501328
1116
129063
Sea Urchin
Strong. purpuratus
XP_795787
1945
218422
P526
P
K
R
E
K
P
P
P
P
P
A
Y
S
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
69.1
83.7
N.A.
78.4
N.A.
N.A.
53.8
N.A.
N.A.
42.2
N.A.
21.3
20.6
21.3
25.4
Protein Similarity:
100
99.6
70.1
89.4
N.A.
85.5
N.A.
N.A.
62.7
N.A.
N.A.
58.5
N.A.
35.7
34.3
35.9
43
P-Site Identity:
100
100
6.6
93.3
N.A.
6.6
N.A.
N.A.
6.6
N.A.
N.A.
6.6
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
20
N.A.
N.A.
13.3
N.A.
N.A.
26.6
N.A.
20
0
0
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
28
10
0
0
0
0
0
19
10
19
10
0
37
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
10
0
0
10
10
0
0
0
0
28
10
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
0
10
10
10
10
0
0
0
0
0
0
0
10
% F
% Gly:
10
0
0
10
0
28
10
10
10
0
0
0
0
10
0
% G
% His:
0
0
0
10
0
0
10
10
0
28
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
10
28
% I
% Lys:
10
19
10
28
55
10
28
10
0
0
28
19
0
0
0
% K
% Leu:
37
10
0
0
0
19
0
0
28
10
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
28
0
10
% M
% Asn:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
10
10
19
10
10
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
10
0
0
0
0
10
0
0
% Q
% Arg:
0
0
37
10
0
0
10
0
19
10
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
28
0
10
0
0
10
0
10
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% T
% Val:
0
19
10
0
19
0
0
0
0
0
0
0
0
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _