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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM3AP All Species: 8.18
Human Site: S69 Identified Species: 18
UniProt: O60318 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60318 NP_003897.2 1980 218405 S69 S G V S H S S S V Q T L G F T
Chimpanzee Pan troglodytes XP_525497 1981 218320 S69 S G V S H S S S V Q T L G F T
Rhesus Macaque Macaca mulatta XP_001118009 1415 157213
Dog Lupus familis XP_537925 1989 218752 S70 S G G S H S A S A Q P L G F S
Cat Felis silvestris
Mouse Mus musculus Q9WUU9 1971 217122 L69 G G S H S S S L P A F G L T Q
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514089 1519 168947
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689234 2082 230356 G91 L G T H P A F G Q P S L G Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U3V9 1370 158161
Honey Bee Apis mellifera XP_395462 961 111706
Nematode Worm Caenorhab. elegans NP_501328 1116 129063
Sea Urchin Strong. purpuratus XP_795787 1945 218422 K71 D R E G E V E K V M S L G E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 69.1 83.7 N.A. 78.4 N.A. N.A. 53.8 N.A. N.A. 42.2 N.A. 21.3 20.6 21.3 25.4
Protein Similarity: 100 99.6 70.1 89.4 N.A. 85.5 N.A. N.A. 62.7 N.A. N.A. 58.5 N.A. 35.7 34.3 35.9 43
P-Site Identity: 100 100 0 66.6 N.A. 20 N.A. N.A. 0 N.A. N.A. 20 N.A. 0 0 0 20
P-Site Similarity: 100 100 0 80 N.A. 20 N.A. N.A. 0 N.A. N.A. 33.3 N.A. 0 0 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 0 10 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 10 0 10 0 0 0 0 0 0 10 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 10 0 0 28 0 % F
% Gly: 10 46 10 10 0 0 0 10 0 0 0 10 46 0 10 % G
% His: 0 0 0 19 28 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % K
% Leu: 10 0 0 0 0 0 0 10 0 0 0 46 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 10 10 10 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 28 0 0 0 10 10 % Q
% Arg: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % R
% Ser: 28 0 10 28 10 37 28 28 0 0 19 0 0 0 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 19 0 0 10 19 % T
% Val: 0 0 19 0 0 10 0 0 28 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _