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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MCM3AP All Species: 19.09
Human Site: S985 Identified Species: 42
UniProt: O60318 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60318 NP_003897.2 1980 218405 S985 T P V C S F N S Q N K Y I G E
Chimpanzee Pan troglodytes XP_525497 1981 218320 S985 T P V C S F N S Q N K Y I G E
Rhesus Macaque Macaca mulatta XP_001118009 1415 157213 I565 K T R K S V F I T R K L T V S
Dog Lupus familis XP_537925 1989 218752 S985 T P V C S F N S Q N K Y I G E
Cat Felis silvestris
Mouse Mus musculus Q9WUU9 1971 217122 S978 T P V C S F N S Q N K Y V G E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514089 1519 168947 D668 L I S D A V V D V L R Q T T A
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689234 2082 230356 S1037 S P V C S F D S N N K Y T G D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9U3V9 1370 158161 Y519 M H T V E T E Y K L P R Q Y E
Honey Bee Apis mellifera XP_395462 961 111706 T111 K N S R S Q I T K I N P E N S
Nematode Worm Caenorhab. elegans NP_501328 1116 129063 I266 D D F E K Y Q I F V K R D G F
Sea Urchin Strong. purpuratus XP_795787 1945 218422 A1010 G T L A I I Q A S P K V I A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 69.1 83.7 N.A. 78.4 N.A. N.A. 53.8 N.A. N.A. 42.2 N.A. 21.3 20.6 21.3 25.4
Protein Similarity: 100 99.6 70.1 89.4 N.A. 85.5 N.A. N.A. 62.7 N.A. N.A. 58.5 N.A. 35.7 34.3 35.9 43
P-Site Identity: 100 100 13.3 100 N.A. 93.3 N.A. N.A. 0 N.A. N.A. 66.6 N.A. 6.6 6.6 13.3 20
P-Site Similarity: 100 100 13.3 100 N.A. 100 N.A. N.A. 13.3 N.A. N.A. 86.6 N.A. 13.3 20 20 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 10 0 0 10 0 0 0 0 0 10 10 % A
% Cys: 0 0 0 46 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 10 0 10 0 0 10 10 0 0 0 0 10 0 10 % D
% Glu: 0 0 0 10 10 0 10 0 0 0 0 0 10 0 55 % E
% Phe: 0 0 10 0 0 46 10 0 10 0 0 0 0 0 10 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 0 0 55 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 10 10 10 19 0 10 0 0 37 0 0 % I
% Lys: 19 0 0 10 10 0 0 0 19 0 73 0 0 0 0 % K
% Leu: 10 0 10 0 0 0 0 0 0 19 0 10 0 0 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 0 37 0 10 46 10 0 0 10 0 % N
% Pro: 0 46 0 0 0 0 0 0 0 10 10 10 0 0 0 % P
% Gln: 0 0 0 0 0 10 19 0 37 0 0 10 10 0 0 % Q
% Arg: 0 0 10 10 0 0 0 0 0 10 10 19 0 0 0 % R
% Ser: 10 0 19 0 64 0 0 46 10 0 0 0 0 0 19 % S
% Thr: 37 19 10 0 0 10 0 10 10 0 0 0 28 10 0 % T
% Val: 0 0 46 10 0 19 10 0 10 10 0 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 10 0 0 0 46 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _