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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1B All Species: 23.33
Human Site: S1227 Identified Species: 42.78
UniProt: O60333 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60333 NP_055889.2 1816 204476 S1227 F P P P M P L S K P V P A T K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 D855 G Q S M S K Y D L L V W F E I
Cat Felis silvestris
Mouse Mus musculus Q60575 1816 204062 S1227 F P P P M P L S K P V P A T K
Rat Rattus norvegicus O88658 1816 204151 S1227 F P P P M P L S R P V P A T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509769 1770 199343 S1181 F P P P M P L S K P V P A T K
Chicken Gallus gallus XP_417608 1757 197902 S1181 F P P P M P L S K P V P A T K
Frog Xenopus laevis Q91784 1226 138905 E674 W K Q Q K T K E V I Q L K E K
Zebra Danio Brachydanio rerio NP_919363 1770 199169 S1179 Y P P P M P L S K P V P A T K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 V1118 L A K H D V L V W F E I C E L
Honey Bee Apis mellifera XP_397276 1682 191012 S1127 P N G E Y V P S V V D H S D D
Nematode Worm Caenorhab. elegans P23678 1584 179603 P1032 P S L V I S T P V K S K K A N
Sea Urchin Strong. purpuratus P46872 699 78679 L147 F L V R V S Y L E I Y N E E V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 G376 E V Q V W R G G E T V P K E K
Conservation
Percent
Protein Identity: 100 N.A. N.A. 75.5 N.A. 97 96.8 N.A. 93.2 92.7 23.8 85.6 N.A. 54.2 56.8 49.3 20.5
Protein Similarity: 100 N.A. N.A. 76.5 N.A. 98.9 98.7 N.A. 95.8 95.1 40.7 91.5 N.A. 69.7 70.5 64.2 28.5
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 93.3 N.A. 100 100 6.6 93.3 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 N.A. N.A. 6.6 N.A. 100 100 N.A. 100 100 13.3 100 N.A. 6.6 13.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 23.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.1
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 20
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 0 0 0 0 47 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 0 0 8 0 0 8 0 0 8 0 0 8 8 % D
% Glu: 8 0 0 8 0 0 0 8 16 0 8 0 8 39 0 % E
% Phe: 47 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % F
% Gly: 8 0 8 0 0 0 8 8 0 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 16 0 8 0 0 8 % I
% Lys: 0 8 8 0 8 8 8 0 39 8 0 8 24 0 62 % K
% Leu: 8 8 8 0 0 0 54 8 8 8 0 8 0 0 8 % L
% Met: 0 0 0 8 47 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 16 47 47 47 0 47 8 8 0 47 0 54 0 0 0 % P
% Gln: 0 8 16 8 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 8 0 8 0 0 8 0 0 0 0 0 0 % R
% Ser: 0 8 8 0 8 16 0 54 0 0 8 0 8 0 0 % S
% Thr: 0 0 0 0 0 8 8 0 0 8 0 0 0 47 0 % T
% Val: 0 8 8 16 8 16 0 8 24 8 62 0 0 0 8 % V
% Trp: 8 0 0 0 8 0 0 0 8 0 0 8 0 0 0 % W
% Tyr: 8 0 0 0 8 0 16 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _