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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAPKBP1 All Species: 1.82
Human Site: S1216 Identified Species: 5
UniProt: O60336 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.25
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60336 NP_001122080.1 1514 163818 S1216 E A S L Q A P S P G A L L S R
Chimpanzee Pan troglodytes XP_001149707 777 82730 A502 G L G S L P P A D G R P S R P
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_544635 1537 166851 P1242 V L Q D E G P P P G P L L L G
Cat Felis silvestris
Mouse Mus musculus Q6NS57 1503 162874 S1205 V P Q D E V P S S R P L L F Q
Rat Rattus norvegicus NP_001102059 1507 163075 Q1217 P S R P L L F Q A E V Q G S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DFF9 1580 174138 R1197 R E E K A I R R R T L P S T L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097050 1539 166881 N1231 G R Y Q K P G N P K T L N P M
Honey Bee Apis mellifera XP_393538 2640 294386 R2288 F M K E K C L R M S H C Q E T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781545 2230 244594 L1879 R R S S T S S L P P S S S E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 50.8 N.A. 90.1 N.A. 86 86.9 N.A. N.A. N.A. 57.7 N.A. N.A. 32.4 27.2 N.A. 31.7
Protein Similarity: 100 50.9 N.A. 92.8 N.A. 90.8 91.2 N.A. N.A. N.A. 71 N.A. N.A. 49.8 38.6 N.A. 45.3
P-Site Identity: 100 13.3 N.A. 33.3 N.A. 26.6 6.6 N.A. N.A. N.A. 0 N.A. N.A. 13.3 0 N.A. 13.3
P-Site Similarity: 100 20 N.A. 40 N.A. 40 13.3 N.A. N.A. N.A. 6.6 N.A. N.A. 26.6 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 0 12 12 0 12 12 0 12 0 0 0 0 % A
% Cys: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % C
% Asp: 0 0 0 23 0 0 0 0 12 0 0 0 0 0 0 % D
% Glu: 12 12 12 12 23 0 0 0 0 12 0 0 0 23 0 % E
% Phe: 12 0 0 0 0 0 12 0 0 0 0 0 0 12 0 % F
% Gly: 23 0 12 0 0 12 12 0 0 34 0 0 12 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % H
% Ile: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 12 12 23 0 0 0 0 12 0 0 0 0 0 % K
% Leu: 0 23 0 12 23 12 12 12 0 0 12 45 34 12 23 % L
% Met: 0 12 0 0 0 0 0 0 12 0 0 0 0 0 12 % M
% Asn: 0 0 0 0 0 0 0 12 0 0 0 0 12 0 0 % N
% Pro: 12 12 0 12 0 23 45 12 45 12 23 23 0 12 12 % P
% Gln: 0 0 23 12 12 0 0 12 0 0 0 12 12 0 12 % Q
% Arg: 23 23 12 0 0 0 12 23 12 12 12 0 0 12 12 % R
% Ser: 0 12 23 23 0 12 12 23 12 12 12 12 34 23 12 % S
% Thr: 0 0 0 0 12 0 0 0 0 12 12 0 0 12 12 % T
% Val: 23 0 0 0 0 12 0 0 0 0 12 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _