KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPKBP1
All Species:
10
Human Site:
S184
Identified Species:
27.5
UniProt:
O60336
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60336
NP_001122080.1
1514
163818
S184
S
S
R
V
T
A
V
S
F
S
E
D
C
S
Y
Chimpanzee
Pan troglodytes
XP_001149707
777
82730
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_544635
1537
166851
S214
S
S
R
V
T
A
V
S
F
S
E
D
C
S
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6NS57
1503
162874
R180
A
S
N
K
V
S
S
R
V
T
A
V
S
F
S
Rat
Rattus norvegicus
NP_001102059
1507
163075
S185
S
S
R
V
T
A
V
S
F
S
E
D
C
S
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6DFF9
1580
174138
V185
V
S
S
K
V
T
A
V
S
F
S
E
D
S
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097050
1539
166881
S202
R
A
N
L
K
M
A
S
N
K
I
S
S
K
V
Honey Bee
Apis mellifera
XP_393538
2640
294386
A585
K
V
S
S
K
V
K
A
V
C
F
A
E
N
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781545
2230
244594
G180
K
I
A
A
Q
V
T
G
L
A
F
S
E
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.8
N.A.
90.1
N.A.
86
86.9
N.A.
N.A.
N.A.
57.7
N.A.
N.A.
32.4
27.2
N.A.
31.7
Protein Similarity:
100
50.9
N.A.
92.8
N.A.
90.8
91.2
N.A.
N.A.
N.A.
71
N.A.
N.A.
49.8
38.6
N.A.
45.3
P-Site Identity:
100
0
N.A.
100
N.A.
6.6
100
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
0
N.A.
100
N.A.
26.6
100
N.A.
N.A.
N.A.
20
N.A.
N.A.
20
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
12
0
34
23
12
0
12
12
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
34
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
34
12
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
34
12
23
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
34
12
23
0
0
12
0
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
23
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
23
0
0
23
23
0
12
0
0
12
0
0
0
12
0
% K
% Leu:
0
0
0
12
0
0
0
0
12
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
23
0
0
0
0
0
12
0
0
0
0
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
0
34
0
0
0
0
12
0
0
0
0
0
0
0
% R
% Ser:
34
56
23
12
0
12
12
45
12
34
12
23
23
45
23
% S
% Thr:
0
0
0
0
34
12
12
0
0
12
0
0
0
0
0
% T
% Val:
12
12
0
34
23
23
34
12
23
0
0
12
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _