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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MARCH6 All Species: 32.73
Human Site: T545 Identified Species: 65.45
UniProt: O60337 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60337 NP_005876.2 910 102545 T545 A L L E Q G H T R Q W L K G L
Chimpanzee Pan troglodytes XP_517630 1263 139378 T898 A L L E Q G H T R Q W L K G L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535791 1209 134667 T844 A L L E Q G H T R Q W L K G L
Cat Felis silvestris
Mouse Mus musculus Q6ZQ89 909 102254 T545 A L L E Q G H T R Q W L K G L
Rat Rattus norvegicus XP_215517 909 102293 T545 A L L E Q G H T R Q W L K G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519170 926 104791 T562 A L L E Q G H T R Q W L K G L
Chicken Gallus gallus XP_419012 981 110091 T617 A L L E Q G H T R Q W L K G L
Frog Xenopus laevis NP_001091317 909 102704 T544 A L L E Q G H T R Q W L K G L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_647715 988 111018 T544 G L L R I W C T A V A W L L G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_492823 1025 117537 G672 A I L E H A N G R G F I K Y G
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002313128 1110 123448 L695 F A I E H F K L R T T I K S L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_001119113 1107 122843 L693 F I I E H F R L R T T I K S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72 N.A. 74.5 N.A. 97.9 97.6 N.A. 92 83.1 90.5 N.A. N.A. 48.2 N.A. 38.8 N.A.
Protein Similarity: 100 72 N.A. 75 N.A. 98.4 98.5 N.A. 94.4 86 95.5 N.A. N.A. 64.5 N.A. 56.7 N.A.
P-Site Identity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 N.A. N.A. 20 N.A. 33.3 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 100 100 N.A. 100 100 100 N.A. N.A. 20 N.A. 60 N.A.
Percent
Protein Identity: 27.6 N.A. N.A. 27.5 N.A. N.A.
Protein Similarity: 46.6 N.A. N.A. 47.5 N.A. N.A.
P-Site Identity: 26.6 N.A. N.A. 26.6 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 75 9 0 0 0 9 0 0 9 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 92 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 17 0 0 0 0 17 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 0 0 0 0 67 0 9 0 9 0 0 0 67 17 % G
% His: 0 0 0 0 25 0 67 0 0 0 0 0 0 0 0 % H
% Ile: 0 17 17 0 9 0 0 0 0 0 0 25 0 0 0 % I
% Lys: 0 0 0 0 0 0 9 0 0 0 0 0 92 0 0 % K
% Leu: 0 75 84 0 0 0 0 17 0 0 0 67 9 9 84 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 67 0 0 0 0 67 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 0 9 0 92 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % S
% Thr: 0 0 0 0 0 0 0 75 0 17 17 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 67 9 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _