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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MARCH6
All Species:
34.85
Human Site:
Y874
Identified Species:
69.7
UniProt:
O60337
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60337
NP_005876.2
910
102545
Y874
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Chimpanzee
Pan troglodytes
XP_517630
1263
139378
Y1227
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535791
1209
134667
Y1173
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ89
909
102254
Y873
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Rat
Rattus norvegicus
XP_215517
909
102293
Y873
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519170
926
104791
Y890
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Chicken
Gallus gallus
XP_419012
981
110091
Y945
V
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Frog
Xenopus laevis
NP_001091317
909
102704
Y873
I
R
Q
F
K
R
L
Y
E
H
I
K
N
D
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647715
988
111018
Y923
I
D
Q
L
K
K
L
Y
L
S
I
K
V
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_492823
1025
117537
W988
S
A
V
V
F
I
R
W
Q
V
V
K
F
R
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313128
1110
123448
H1047
H
V
W
F
T
N
L
H
N
S
I
R
D
D
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_001119113
1107
122843
H1047
H
V
W
F
R
N
L
H
N
S
I
R
D
D
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72
N.A.
74.5
N.A.
97.9
97.6
N.A.
92
83.1
90.5
N.A.
N.A.
48.2
N.A.
38.8
N.A.
Protein Similarity:
100
72
N.A.
75
N.A.
98.4
98.5
N.A.
94.4
86
95.5
N.A.
N.A.
64.5
N.A.
56.7
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
93.3
N.A.
N.A.
53.3
N.A.
6.6
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
100
100
100
N.A.
N.A.
66.6
N.A.
33.3
N.A.
Percent
Protein Identity:
27.6
N.A.
N.A.
27.5
N.A.
N.A.
Protein Similarity:
46.6
N.A.
N.A.
47.5
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
53.3
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
0
0
0
17
92
0
% D
% Glu:
0
0
0
0
0
0
0
0
67
0
0
0
0
0
9
% E
% Phe:
0
0
0
84
9
0
0
0
0
0
0
0
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
17
0
0
0
0
0
0
17
0
67
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
9
0
0
0
0
92
0
0
0
0
% I
% Lys:
0
0
0
0
75
9
0
0
0
0
0
84
0
0
75
% K
% Leu:
0
0
0
9
0
0
92
0
9
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
17
0
0
17
0
0
0
67
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
75
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
67
0
0
9
67
9
0
0
0
0
17
0
9
17
% R
% Ser:
9
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% T
% Val:
59
17
9
9
0
0
0
0
0
9
9
0
9
0
0
% V
% Trp:
0
0
17
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _