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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM1A All Species: 31.52
Human Site: S523 Identified Species: 63.03
UniProt: O60341 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60341 NP_001009999.1 852 92903 S523 P S D V Y L S S R D R Q I L D
Chimpanzee Pan troglodytes XP_513190 828 91745 S499 P S D V Y L S S R D R Q I L D
Rhesus Macaque Macaca mulatta XP_001111525 998 108662 S669 P S D V Y L S S R D R Q I L D
Dog Lupus familis XP_866610 853 92820 S524 P S D V Y L S S R D R Q I L D
Cat Felis silvestris
Mouse Mus musculus Q6ZQ88 853 92832 S524 P S D V Y L S S R D R Q I L D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516745 677 75850 L387 L A E T Q A K L E E K L Q E L
Chicken Gallus gallus XP_417719 750 82930 G460 D D D F E F T G S H L T V R N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665248 867 95507 S537 P S D V Y L S S R D R Q I L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW97 890 98370 S516 P S D V Y L S S R D R L I L D
Honey Bee Apis mellifera XP_001122201 584 65568 E294 T V P K D K D E M V E R E F N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779917 848 93805 S528 P S D V Y L S S R D R Q I L D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50264 508 57787 L217 Q S F P Q N W L K L S C E V K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 85.1 99 N.A. 98.1 N.A. N.A. 76.8 82.3 N.A. 83.1 N.A. 48.7 41.9 N.A. 65.3
Protein Similarity: 100 85.2 85.1 99.1 N.A. 98.5 N.A. N.A. 77.5 84.2 N.A. 87.6 N.A. 64.9 52.7 N.A. 77.8
P-Site Identity: 100 100 100 100 N.A. 100 N.A. N.A. 0 6.6 N.A. 100 N.A. 93.3 0 N.A. 100
P-Site Similarity: 100 100 100 100 N.A. 100 N.A. N.A. 26.6 26.6 N.A. 100 N.A. 93.3 13.3 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 9 9 75 0 9 0 9 0 0 67 0 0 0 0 67 % D
% Glu: 0 0 9 0 9 0 0 9 9 9 9 0 17 9 0 % E
% Phe: 0 0 9 9 0 9 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 67 0 0 % I
% Lys: 0 0 0 9 0 9 9 0 9 0 9 0 0 0 9 % K
% Leu: 9 0 0 0 0 67 0 17 0 9 9 17 0 67 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 17 % N
% Pro: 67 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 0 0 0 17 0 0 0 0 0 0 59 9 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 67 0 67 9 0 9 0 % R
% Ser: 0 75 0 0 0 0 67 67 9 0 9 0 0 0 0 % S
% Thr: 9 0 0 9 0 0 9 0 0 0 0 9 0 0 0 % T
% Val: 0 9 0 67 0 0 0 0 0 9 0 0 9 9 0 % V
% Trp: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _