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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KDM1A All Species: 21.82
Human Site: Y255 Identified Species: 43.64
UniProt: O60341 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60341 NP_001009999.1 852 92903 Y255 L V H R V H S Y L E R H G L I
Chimpanzee Pan troglodytes XP_513190 828 91745 K243 F G I Y K R I K P L P T K K T
Rhesus Macaque Macaca mulatta XP_001111525 998 108662 Y397 L V H R V H S Y L E R H G L I
Dog Lupus familis XP_866610 853 92820 Y256 L V H R V H S Y L E R H G L I
Cat Felis silvestris
Mouse Mus musculus Q6ZQ88 853 92832 Y256 L V H R V H S Y L E R H G L I
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516745 677 75850 K159 R V K P L P T K K T G K V I I
Chicken Gallus gallus XP_417719 750 82930 V232 A D L G A M V V T G L G G N P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665248 867 95507 Y263 L V H R I H S Y L E R H G F I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW97 890 98370 F241 L V R R V H S F L E R H G F I
Honey Bee Apis mellifera XP_001122201 584 65568 P66 S V P T S S A P R I E V K E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_779917 848 93805 Y255 L I V R V H A Y L E R H G Y I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P50264 508 57787
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83 85.1 99 N.A. 98.1 N.A. N.A. 76.8 82.3 N.A. 83.1 N.A. 48.7 41.9 N.A. 65.3
Protein Similarity: 100 85.2 85.1 99.1 N.A. 98.5 N.A. N.A. 77.5 84.2 N.A. 87.6 N.A. 64.9 52.7 N.A. 77.8
P-Site Identity: 100 0 100 100 N.A. 100 N.A. N.A. 13.3 6.6 N.A. 86.6 N.A. 80 6.6 N.A. 73.3
P-Site Similarity: 100 0 100 100 N.A. 100 N.A. N.A. 33.3 6.6 N.A. 93.3 N.A. 86.6 13.3 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 0 17 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 59 9 0 0 9 9 % E
% Phe: 9 0 0 0 0 0 0 9 0 0 0 0 0 17 0 % F
% Gly: 0 9 0 9 0 0 0 0 0 9 9 9 67 0 0 % G
% His: 0 0 42 0 0 59 0 0 0 0 0 59 0 0 0 % H
% Ile: 0 9 9 0 9 0 9 0 0 9 0 0 0 9 67 % I
% Lys: 0 0 9 0 9 0 0 17 9 0 0 9 17 9 0 % K
% Leu: 59 0 9 0 9 0 0 0 59 9 9 0 0 34 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % N
% Pro: 0 0 9 9 0 9 0 9 9 0 9 0 0 0 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 0 9 59 0 9 0 0 9 0 59 0 0 0 0 % R
% Ser: 9 0 0 0 9 9 50 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 9 0 0 9 0 9 9 0 9 0 0 9 % T
% Val: 0 67 9 0 50 0 9 9 0 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 0 0 0 50 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _