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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D4
All Species:
13.64
Human Site:
S370
Identified Species:
50
UniProt:
O60343
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60343
NP_055647.2
1298
146563
S370
R
F
E
I
N
L
I
S
P
D
T
K
S
V
V
Chimpanzee
Pan troglodytes
XP_522684
1535
172066
S606
R
F
E
I
N
L
I
S
P
D
T
K
S
V
V
Rhesus Macaque
Macaca mulatta
NP_001165894
1299
146547
S370
R
F
E
I
N
L
I
S
P
D
T
K
S
V
V
Dog
Lupus familis
XP_542613
1075
122345
V212
Q
C
A
S
E
S
L
V
D
E
V
M
L
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYJ6
1307
147432
S377
R
F
E
I
N
L
I
S
P
D
T
K
S
V
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509000
567
65663
Chicken
Gallus gallus
Q5ZJ17
816
92547
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.2
97.5
78.6
N.A.
89.8
N.A.
N.A.
38.2
23
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
84.3
98.5
80.5
N.A.
94
N.A.
N.A.
40.9
36.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
26.6
N.A.
100
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
58
0
0
0
0
0
% D
% Glu:
0
0
58
0
15
0
0
0
0
15
0
0
0
0
0
% E
% Phe:
0
58
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
58
0
0
58
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
58
0
0
0
% K
% Leu:
0
0
0
0
0
58
15
0
0
0
0
0
15
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% M
% Asn:
0
0
0
0
58
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
58
0
0
0
0
0
0
% P
% Gln:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
58
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
15
0
15
0
58
0
0
0
0
58
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
58
0
0
15
0
% T
% Val:
0
0
0
0
0
0
0
15
0
0
15
0
0
58
58
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _