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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHLPP1
All Species:
4.55
Human Site:
S335
Identified Species:
12.5
UniProt:
O60346
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60346
NP_919431.1
1717
184672
S335
P
F
V
G
G
P
V
S
S
P
R
A
P
R
P
Chimpanzee
Pan troglodytes
XP_523952
1722
185311
S336
P
F
V
G
G
P
V
S
S
P
R
A
P
R
P
Rhesus Macaque
Macaca mulatta
XP_001094216
1359
149772
P131
R
L
E
A
E
E
K
P
L
Q
I
Q
N
D
Y
Dog
Lupus familis
XP_533384
1335
146002
G107
T
L
Y
V
Q
L
H
G
E
A
T
R
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CHE4
1687
182348
W278
L
P
L
P
G
G
A
W
T
R
C
A
P
R
I
Rat
Rattus norvegicus
Q9WTR8
1696
183345
C302
E
L
F
A
G
G
P
C
S
P
S
R
A
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509377
1323
146060
R95
R
R
L
E
P
T
E
R
P
L
Q
I
V
Y
E
Chicken
Gallus gallus
XP_418990
1247
138448
G19
G
S
A
G
G
A
G
G
S
A
A
A
V
H
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700869
1023
110865
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
77.8
72.3
N.A.
87.2
87.4
N.A.
43.2
65
N.A.
31.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
78.5
74.4
N.A.
90.3
90.3
N.A.
56.9
68.7
N.A.
41.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
26.6
20
N.A.
0
33.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
0
N.A.
40
20
N.A.
13.3
33.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
23
0
12
12
0
0
23
12
45
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
12
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% D
% Glu:
12
0
12
12
12
12
12
0
12
0
0
0
0
0
23
% E
% Phe:
0
23
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
34
56
23
12
23
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
12
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
12
0
0
12
% I
% Lys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% K
% Leu:
12
34
23
0
0
12
0
0
12
12
0
0
0
12
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
23
12
0
12
12
23
12
12
12
34
0
0
34
12
34
% P
% Gln:
0
0
0
0
12
0
0
0
0
12
12
12
0
0
0
% Q
% Arg:
23
12
0
0
0
0
0
12
0
12
23
23
12
34
12
% R
% Ser:
0
12
0
0
0
0
0
23
45
0
12
0
0
0
0
% S
% Thr:
12
0
0
0
0
12
0
0
12
0
12
0
0
0
0
% T
% Val:
0
0
23
12
0
0
23
0
0
0
0
0
23
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _