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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D12
All Species:
21.82
Human Site:
T659
Identified Species:
80
UniProt:
O60347
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60347
NP_056003.1
775
85626
T659
H
F
K
S
Y
S
L
T
P
D
I
Y
L
I
D
Chimpanzee
Pan troglodytes
XP_507936
862
94173
T746
H
F
K
S
Y
S
L
T
P
D
I
Y
L
I
D
Rhesus Macaque
Macaca mulatta
XP_001090278
732
80999
T616
H
F
K
S
Y
S
L
T
P
D
I
Y
L
I
D
Dog
Lupus familis
XP_849591
772
84316
T656
H
F
K
S
Y
S
L
T
P
D
I
Y
L
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6A039
696
76792
T580
H
F
K
S
Y
N
L
T
P
D
I
Y
L
I
D
Rat
Rattus norvegicus
Q5CD77
694
78190
T579
H
F
K
K
N
N
L
T
A
D
I
Y
L
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395767
620
69571
G516
F
S
H
F
T
V
A
G
L
S
P
D
L
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.5
81.6
87.6
N.A.
78.1
47.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.4
N.A.
N.A.
Protein Similarity:
100
87.3
84.5
90.4
N.A.
81
61.1
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
48.2
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
15
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
86
0
15
0
0
86
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
15
86
0
15
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% G
% His:
86
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
86
0
0
86
0
% I
% Lys:
0
0
86
15
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
86
0
15
0
0
0
100
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
15
29
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
72
0
15
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
72
0
58
0
0
0
15
0
0
0
0
0
% S
% Thr:
0
0
0
0
15
0
0
86
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
72
0
0
0
0
0
0
86
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _