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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOBOX All Species: 0.3
Human Site: S595 Identified Species: 0.83
UniProt: O60393 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60393 NP_001073882 691 73906 S595 A G N I G T A S W S D P C L P
Chimpanzee Pan troglodytes XP_001149985 365 38386 P282 S M G M I R K P G S E D K L A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539833 611 65140 L528 C P Q T L G A L P G G E G Y L
Cat Felis silvestris
Mouse Mus musculus Q8VIH1 527 57546 Y444 P P F P R P H Y P Q A L G Q P
Rat Rattus norvegicus P97830 530 53861 A447 R R S P E V V A S P G P P A P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q9PVX0 317 34038 P234 G A A L Q S L P G F A A P P Q
Frog Xenopus laevis Q91574 335 37508 R252 V T S C M L P R E P S S C M T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q06453 408 43639 I325 S P Q H L V G I A L T Q Q A S
Honey Bee Apis mellifera XP_624630 369 40270 G286 P P P L L P P G M P L P Y T S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.5 N.A. 44.2 N.A. 45.1 20.8 N.A. N.A. 21.7 20.4 N.A. N.A. 20.9 24 N.A. N.A.
Protein Similarity: 100 30.8 N.A. 53.6 N.A. 53.9 30.9 N.A. N.A. 28.5 31.6 N.A. N.A. 30.1 33 N.A. N.A.
P-Site Identity: 100 13.3 N.A. 6.6 N.A. 6.6 13.3 N.A. N.A. 0 6.6 N.A. N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 33.3 N.A. 6.6 N.A. 6.6 26.6 N.A. N.A. 13.3 20 N.A. N.A. 6.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 12 0 0 0 23 12 12 0 23 12 0 23 12 % A
% Cys: 12 0 0 12 0 0 0 0 0 0 0 0 23 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % D
% Glu: 0 0 0 0 12 0 0 0 12 0 12 12 0 0 0 % E
% Phe: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % F
% Gly: 12 12 12 0 12 12 12 12 23 12 23 0 23 0 0 % G
% His: 0 0 0 12 0 0 12 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 12 12 0 0 12 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 12 0 0 0 0 0 12 0 0 % K
% Leu: 0 0 0 23 34 12 12 12 0 12 12 12 0 23 12 % L
% Met: 0 12 0 12 12 0 0 0 12 0 0 0 0 12 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 23 45 12 23 0 23 23 23 23 34 0 34 23 12 34 % P
% Gln: 0 0 23 0 12 0 0 0 0 12 0 12 12 12 12 % Q
% Arg: 12 12 0 0 12 12 0 12 0 0 0 0 0 0 0 % R
% Ser: 23 0 23 0 0 12 0 12 12 23 12 12 0 0 23 % S
% Thr: 0 12 0 12 0 12 0 0 0 0 12 0 0 12 12 % T
% Val: 12 0 0 0 0 23 12 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 12 0 0 0 0 12 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _