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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP8B3 All Species: 4.85
Human Site: S1288 Identified Species: 10.67
UniProt: O60423 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60423 NP_620168.1 1310 148031 S1288 R R G P G V S S D I A S E S L
Chimpanzee Pan troglodytes XP_001139503 1201 137341 K1180 S G R S I R K K R S P L D A I
Rhesus Macaque Macaca mulatta XP_001085877 1239 141305 L1218 H K H G F G A L I T S G Q T M
Dog Lupus familis XP_855076 1367 153870 S1248 R R A P G P D S D L L A H E A
Cat Felis silvestris
Mouse Mus musculus Q148W0 1251 143779 S1222 R G Y A D L I S S G R S I R K
Rat Rattus norvegicus XP_234937 1340 152922 D1319 W K G P L L R D S A S S R S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510687 1258 144573 D1237 R K K R S P L D S V L G E A A
Chicken Gallus gallus XP_425888 1253 142301 D1232 N S T H A T N D I C A T T A L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_687715 1223 139712 T1202 A P G E K G T T S A N S R P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9XIE6 1213 137734 P1192 S Q L G I Y A P Q K A W D V A
Baker's Yeast Sacchar. cerevisiae P39524 1355 153826 A1326 G S N D F E S A E P F I E N P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 43.3 41.5 56.6 N.A. 44.8 64.7 N.A. 44.6 52.3 N.A. 41.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 62.2 59.6 68.9 N.A. 63.2 76.6 N.A. 62.6 68.5 N.A. 61.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 0 40 N.A. 20 26.6 N.A. 13.3 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 20 40 53.3 N.A. 26.6 46.6 N.A. 33.3 33.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 34.9 33.8 N.A.
Protein Similarity: N.A. N.A. N.A. 53.5 52.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 10 10 0 19 10 0 19 28 10 0 28 28 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 10 10 0 10 28 19 0 0 0 19 0 0 % D
% Glu: 0 0 0 10 0 10 0 0 10 0 0 0 28 10 0 % E
% Phe: 0 0 0 0 19 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 10 19 28 19 19 19 0 0 0 10 0 19 0 0 0 % G
% His: 10 0 10 10 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 0 0 19 0 10 0 19 10 0 10 10 0 10 % I
% Lys: 0 28 10 0 10 0 10 10 0 10 0 0 0 0 10 % K
% Leu: 0 0 10 0 10 19 10 10 0 10 19 10 0 0 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 10 0 10 0 0 0 10 0 0 0 10 0 0 10 0 % N
% Pro: 0 10 0 28 0 19 0 10 0 10 10 0 0 10 10 % P
% Gln: 0 10 0 0 0 0 0 0 10 0 0 0 10 0 0 % Q
% Arg: 37 19 10 10 0 10 10 0 10 0 10 0 19 10 0 % R
% Ser: 19 19 0 10 10 0 19 28 37 10 19 37 0 19 19 % S
% Thr: 0 0 10 0 0 10 10 10 0 10 0 10 10 10 0 % T
% Val: 0 0 0 0 0 10 0 0 0 10 0 0 0 10 0 % V
% Trp: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _