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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP8B3
All Species:
4.55
Human Site:
S639
Identified Species:
10
UniProt:
O60423
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60423
NP_620168.1
1310
148031
S639
L
A
I
M
D
F
N
S
T
R
K
R
M
S
V
Chimpanzee
Pan troglodytes
XP_001139503
1201
137341
A571
I
K
L
Y
C
K
G
A
D
T
V
I
Y
E
R
Rhesus Macaque
Macaca mulatta
XP_001085877
1239
141305
Q607
M
G
K
T
R
V
Y
Q
L
L
T
I
L
D
F
Dog
Lupus familis
XP_855076
1367
153870
N605
R
M
S
V
L
V
R
N
P
E
G
S
I
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q148W0
1251
143779
R600
I
L
D
F
N
S
D
R
K
R
M
S
I
I
V
Rat
Rattus norvegicus
XP_234937
1340
152922
L647
Y
N
K
L
E
Q
N
L
Q
L
L
G
V
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510687
1258
144573
R600
I
L
D
F
N
S
E
R
K
R
M
S
I
I
V
Chicken
Gallus gallus
XP_425888
1253
142301
E611
L
S
E
A
E
Y
D
E
W
G
R
R
H
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687715
1223
139712
T593
L
Y
S
K
G
A
D
T
I
L
F
D
R
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XIE6
1213
137734
R583
K
R
Q
S
V
V
C
R
F
P
D
G
R
L
V
Baker's Yeast
Sacchar. cerevisiae
P39524
1355
153826
S700
L
N
I
C
E
F
N
S
T
R
K
R
M
S
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.3
41.5
56.6
N.A.
44.8
64.7
N.A.
44.6
52.3
N.A.
41.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
62.2
59.6
68.9
N.A.
63.2
76.6
N.A.
62.6
68.5
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
0
N.A.
13.3
6.6
N.A.
13.3
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
13.3
26.6
N.A.
40
33.3
N.A.
33.3
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
34.9
33.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.5
52.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
73.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
10
0
10
0
0
0
0
0
0
19
% A
% Cys:
0
0
0
10
10
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
10
0
28
0
10
0
10
10
0
10
10
% D
% Glu:
0
0
10
0
28
0
10
10
0
10
0
0
0
10
0
% E
% Phe:
0
0
0
19
0
19
0
0
10
0
10
0
0
0
10
% F
% Gly:
0
10
0
0
10
0
10
0
0
10
10
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
28
0
19
0
0
0
0
0
10
0
0
19
28
19
0
% I
% Lys:
10
10
19
10
0
10
0
0
19
0
19
0
0
0
0
% K
% Leu:
37
19
10
10
10
0
0
10
10
28
10
0
10
19
10
% L
% Met:
10
10
0
10
0
0
0
0
0
0
19
0
19
0
0
% M
% Asn:
0
19
0
0
19
0
28
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
10
0
10
10
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
10
0
10
28
0
37
10
28
19
10
10
% R
% Ser:
0
10
19
10
0
19
0
19
0
0
0
28
0
19
0
% S
% Thr:
0
0
0
10
0
0
0
10
19
10
10
0
0
10
0
% T
% Val:
0
0
0
10
10
28
0
0
0
0
10
0
10
0
46
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
10
10
0
10
0
10
10
0
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _